Insinuating cocktailed components in biocompatible-nanoparticles could act as an impressive neo-adjuvant strategy to combat COVID-19
- Title
- Insinuating cocktailed components in biocompatible-nanoparticles could act as an impressive neo-adjuvant strategy to combat COVID-19
- Creator
- Bhotla H.K.; Balasubramanian B.; Arumugam V.A.; Pushparaj K.; Easwaran M.; Baskaran R.; Saravanan M.; Pappusamy M.; Meyyazhagan A.
- Description
- The novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) spread, freezes all sectors, and was declared as a life-threatening disease by the World Health Organization on Jan 30, 2020. So far, no specific drugs are identified or approved for treating SARS-CoV-2. In the past few years, nanomaterials are in the limelight for their ability to deliver the drugs effectively and selectively like siRNA to target/prime infection sites, and benefits us to visualize the particular regions, treatment reactions via non-intruding imaging techniques. As intranasal delivery interacts directly to the infection site with minimal side effects on the healthy cell, we postulate to administer a mixture of few polyherbal formulations like the golden spice curcumin, sitopaladi churna (SPC), and kaempferol in zein-chitosan nanoparticles as a life-saving measure for treating Coronavirus disease (COVID-19) cases. This viewpoint will shed light on the antiviral role of curcumin, SPC, and kaempferol zein-chitosan nanoparticle to modulate immune responses and observe its curative approach to the current pandemic COVID. 2021, Visagaa Publishing House. All rights reserved.
- Source
- Natural Resources for Human Health, Vol-1, No. 1, pp. 3-7.
- Date
- 2021-01-01
- Publisher
- Visagaa Publishing House
- Subject
- Coronavirus 2; Coronavirus disease 19; Curcumin; Kaempferol; Severe Acute Respiratory Syndrome; Sitopaladi churna (SPC); ZeinChitosan nanoparticle
- Coverage
- Bhotla H.K., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bengaluru, 560029, India; Balasubramanian B., Department of Food Science and Biotechnology, College of Life Science, Sejong University, Seoul, 05006, South Korea; Arumugam V.A., Medical Genetics and Epigenetics Laboratory, Department of Human Genetics and Molecular Biology, Bharathiar University, Tamil Nadu, Coimbatore, 641046, India; Pushparaj K., Department of Zoology, School of Biosciences, Avinashilingam Institute for Home Science and Higher Education for Women, Tamil Nadu, Coimbatore, 641 043, India; Easwaran M., Nutritional Improvement of Crops, International Centre for Genetic Engineering and Biotechnology, New Delhi, 110067, India; Baskaran R., Department of Bioinformatics and Medical Engineering, Asia University, Taichung, Taiwan; Saravanan M., Department of Microbiology and Immunology, Division of Biomedical Sciences, School of Medicine, College of Health Science, Mekelle University, Mekelle, 1871, Ethiopia, Department of Pharmacology, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha Dental College, Chennai, 600077, India; Pappusamy M., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bengaluru, 560029, India; Meyyazhagan A., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bengaluru, 560029, India
- Rights
- All Open Access; Hybrid Gold Open Access
- Relation
- ISSN: 25831194
- Format
- Online
- Language
- English
- Type
- Article
Collection
Citation
Bhotla H.K.; Balasubramanian B.; Arumugam V.A.; Pushparaj K.; Easwaran M.; Baskaran R.; Saravanan M.; Pappusamy M.; Meyyazhagan A., “Insinuating cocktailed components in biocompatible-nanoparticles could act as an impressive neo-adjuvant strategy to combat COVID-19,” CHRIST (Deemed To Be University) Institutional Repository, accessed February 25, 2025, https://archives.christuniversity.in/items/show/15963.