Anti-bacterial and biocompatibility properties of green synthesized silver nanoparticles using Parkia biglandulosa (Fabales:Fabaceae) leaf extract
- Title
- Anti-bacterial and biocompatibility properties of green synthesized silver nanoparticles using Parkia biglandulosa (Fabales:Fabaceae) leaf extract
- Creator
- John A.; Shaji A.; Velayudhannair K.; M N.; Krishnamoorthy G.
- Description
- The biosynthesis of silver nanoparticles is considered to be a feasible, green, and eco-friendly method. Silver nanoparticles (AgNPs) were synthesized using badminton ball tree (Parkia biglandulosa) leaf extract and their significant physiochemical properties were characterized. The aqueous extract of the leaf of P. biglandulosa act as a reducing as well as capping agent for the reduction of Ag+ ?ions. FTIR analysis was conducted to find out the compounds that were liable for the bio-reduction of silver ions and to study the functional groups present in P. bigalandulosa leaf extract. The biologically reduced silver nanoparticles showed a surface plasmon resonance at 439 ?nm as studied from the UVvisible absorption spectrum. TEM studies confirmed the shape of the nanoparticles to be spherical with an average diameter of 15 ?nm. The anti-bacterial properties of the prepared nanoparticles were tested against Bacillus cereus by well plate method. Biosynthesized silver nanoparticles (PbAgNPs) at 0.02 ?M concentration showed the most antibacterial activity with a zone of inhibition of 7 ?mm. The high biocompatibility of the PbAgNPs by using human skin fibroblast cell line was evaluated by Alamar Blue reduction assay. The PbAgNPs had shown the highest cell viability when compared to native nanoparticles, meanwhile, a significant increase in cell viability was noted for the nanoparticles. The biosynthetic approach for synthesis was found to be a facile, rapid, single-step, safe, and effective alternative to the conventional physical/chemical methods. 2021 The Authors
- Source
- Current Research in Green and Sustainable Chemistry, Vol-4
- Date
- 2021-01-01
- Publisher
- Elsevier B.V.
- Subject
- Antibacterial activity; B. cereus; Biocompatibility; P. biglandulosa; Silver nanoparticles
- Coverage
- John A., Department of Chemistry, CHRIST (Deemed to be University), Hosur Road, Bengaluru, 560 029, Karnataka, India; Shaji A., Department of Chemistry, CHRIST (Deemed to be University), Hosur Road, Bengaluru, 560 029, Karnataka, India; Velayudhannair K., Department of Life Sciences, CHRIST (Deemed to be University), Hosur Road, Bengaluru, 560029, Karnataka, India; M N., Department of Chemistry, CHRIST (Deemed to be University), Hosur Road, Bengaluru, 560 029, Karnataka, India; Krishnamoorthy G., Natural Products Chemistry Groups, Chemical Science & Technology Division, CSIR-North East Institute of Science & Technology (NEIST), Jorhat, 785 006, Assam, India
- Rights
- All Open Access; Gold Open Access
- Relation
- ISSN: 26660865
- Format
- Online
- Language
- English
- Type
- Article
Collection
Citation
John A.; Shaji A.; Velayudhannair K.; M N.; Krishnamoorthy G., “Anti-bacterial and biocompatibility properties of green synthesized silver nanoparticles using Parkia biglandulosa (Fabales:Fabaceae) leaf extract,” CHRIST (Deemed To Be University) Institutional Repository, accessed February 25, 2025, https://archives.christuniversity.in/items/show/16054.