Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Articles Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Employing bioactive compounds derived from Ipomoea obscura (L.) to evaluate potential inhibitor for SARS-CoV-2 main protease and ACE2 protein Subject The topic of the resource ADME; GC-MS; Ipomoea Obscura (L.); Molecular docking; SARS-CoV-2 Description An account of the resource Angiotensin converting enzyme 2 (ACE2) and main protease (MPro) are significant target proteins, mainly involved in the attachment of viral genome to host cells and aid in replication of severe acute respiratory syndrome-coronaviruses or SARS-CoV genome. In the present study, we identified 11 potent bioactive compounds from ethanolic leaf extract of Ipomoea obscura (L.) by using GC-MS analysis. These potential bioactive compounds were considered for molecular docking studies against ACE2 and MPro target proteins to determine the antiviral effects against SARS-COV. Results exhibits that among 11 compounds from I. obscura (L.), urso-deoxycholic acid, demeclocycline, tetracycline, chlorotetracycline, and ethyl iso-allocholate had potential viral inhibitory activity. Hence, the present findings suggested that chemical constitution present in I. obscura (L.) will address inhibition of corona viral replication in host cells. 2020 The Authors. Food Frontiers published by NCU, NWU, JSU, ZJU &amp; FAFU and John Wiley &amp; Sons Australia, Ltd. Creator An entity primarily responsible for making the resource Poochi S.P.; Easwaran M.; Balasubramanian B.; Anbuselvam M.; Meyyazhagan A.; Park S.; Bhotla H.K.; Anbuselvam J.; Arumugam V.A.; Keshavarao S.; Kanniyappan G.V.; Pappusamy M.; Kaul T. Source A related resource from which the described resource is derived Food Frontiers, Vol-1, No. 2, pp. 168-179. Publisher An entity responsible for making the resource available John Wiley and Sons Inc Date A point or period of time associated with an event in the lifecycle of the resource 2020-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1002/fft2.29" target="_blank" rel="noreferrer noopener">https://doi.org/10.1002/fft2.29</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099958364&amp;doi=10.1002%2Ffft2.29&amp;partnerID=40&amp;md5=e8bc8d52cd17c7b35444b8504b942e32" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099958364&amp;doi=10.1002%2ffft2.29&amp;partnerID=40&amp;md5=e8bc8d52cd17c7b35444b8504b942e32</a> Rights Information about rights held in and over the resource All Open Access; Gold Open Access; Green Open Access Relation A related resource ISSN: 26438429 Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Article Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Poochi S.P., Department of Biochemistry and Bioinformatics, Karpagam Academy of Higher Education, Coimbatore, 641021, India; Easwaran M., Nutritional Improvement of Crops, International Centre for Genetic Engineering and Biotechnology, New Delhi, 110067, India; Balasubramanian B., Department of Food Science and Biotechnology, College of Life Science, Sejong University, Seoul, 05006, South Korea; Anbuselvam M., Department of Biotechnology, Selvamm College of Arts and Science, Namakkal, 637003, India; Meyyazhagan A., Euroespes Biomedical Research Centre, International Centre of Neuroscience and Genomic Medicine, Corunna, 15165, Spain, Department of Life Sciences, Christ (Deemed to be University), Bangalore, 560029, India; Park S., Department of Food Science and Biotechnology, College of Life Science, Sejong University, Seoul, 05006, South Korea; Bhotla H.K., Department of Medicine, Section of Internal and Cardiovascular Medicine, University of Perugia, Perugia, Italy; Anbuselvam J., Department of Animal Science, Bharathidasan University, Tiruchirappalli, 620024, India; Arumugam V.A., Medical Genetics and Epigenetics Laboratory, Department of Human Genetics and Molecular Biology, Bharathiar University, Tamil Nadu, Coimbatore, India; Keshavarao S., and Emeritus (Rtd.), Human Genetics Laboratory, Department of Zoology, School of Life Sciences, Bharathiar University, Tamil Nadu, Coimbatore, 46, India; Kanniyappan G.V., Department of Chemistry, College of Natural and Computational Sciences, Aksum University, Ethiopia; Pappusamy M., Department of Life Sciences, Christ (Deemed to be University), Bangalore, 560029, India; Kaul T., Nutritional Improvement of Crops, International Centre for Genetic Engineering and Biotechnology, New Delhi, 110067, India