Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Articles Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Analysis of chromosomal aberrations and micronuclei in type 2 diabetes mellitus patients Subject The topic of the resource Chromosomal aberration assay-micronucleus assay-oxidative stress-type 2 diabetes mellitus Description An account of the resource Introduction: Type 2 diabetes mellitus is a metabolic disorder characterized by insulin resistance and disrupted insulin secretion. It is often linked to injuries, malfunction and failure of several organs in the long term. The elevated chromosomal disruptions and genetic complications in diabetic patients are due to the increased production of reactive oxygen species. Materials and Methods: The current study used chromosomal aberration assay and micronucleus assay to analyze the extent of abnormalities in the subjects. Results: The results showed increase in frequency of chromosomal aberrations in diabetic patients when compared to the control group (2.761.65 and 0.470.75 respectively). They also showed higher levels of micronuclei formation than the control participants (13.288.63 and 4.128.89 respectively). The correlation analysis indicated positive relationship between total aberrations and duration of diabetes. Conclusion: These results indicate that diabetes is associated with genomic instability and studies at a genetic level can be employed for early detection. 2020, West Asia Organization for Cancer Prevention. Creator An entity primarily responsible for making the resource Manikantan P.; Rajesh N.; Philip A.M. Source A related resource from which the described resource is derived Asia Pacific Journal of Cancer Biology, Vol-5, No. 1, pp. 15-18. Publisher An entity responsible for making the resource available West Asia Organization for Cancer Prevention Date A point or period of time associated with an event in the lifecycle of the resource 2020-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.31557/APJCB.2020.5.1.15-18" target="_blank" rel="noreferrer noopener">https://doi.org/10.31557/APJCB.2020.5.1.15-18</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85123601619&amp;doi=10.31557%2FAPJCB.2020.5.1.15-18&amp;partnerID=40&amp;md5=887ad80d8de3391a2a1acb73dbbe676c" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85123601619&amp;doi=10.31557%2fAPJCB.2020.5.1.15-18&amp;partnerID=40&amp;md5=887ad80d8de3391a2a1acb73dbbe676c</a> Rights Information about rights held in and over the resource All Open Access; Gold Open Access Relation A related resource ISSN: 25384635 Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Article Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Manikantan P., Department of Life Sciences, CHRIST (Deemed to be University), Bengaluru, Karnataka, India; Rajesh N., Department of Life Sciences, CHRIST (Deemed to be University), Bengaluru, Karnataka, India; Philip A.M., Department of Life Sciences, CHRIST (Deemed to be University), Bengaluru, Karnataka, India