Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Articles Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Chlorin e6 decorated doxorubicin encapsulated chitosan nanoparticles for photo-controlled cancer drug delivery Subject The topic of the resource Chitosan nanoparticles; Chlorin e6; Doxorubicin; Photosensitizer; Photostability Description An account of the resource In the study we have reported the physico-chemical, photophysical and morphological properties of chlorin e6 (Ce6) decorated doxorubicin (DOX) encapsulated chitosan (CS)-tripolyphosphate (TPP) nanoparticles which prepared by ionotropic gelation method. The Ce6 physically loaded onto the nanoparticles by self-assembly of CS with TPP-DOX under aqueous conditions. The results from DLS studies highlights the prepared nanoparticles that possess the size in the range of 80120 nm. with negatively charged of ?6 mV. The SEM and AFM images showed 80120 nm size while the average size of the Ce6 decorated nanoparticles was found to be around 100130 nm. The absorption spectra of Ce6 decorated nanoparticles are similar when compared to free Ce6 which suggest there is no change in the Ce6 chromophore upon decoration. This nanoparticle showed high photostability and singlet oxygen generation (SOG). The Ce6 decorated and DOX encapsulated nanoparticles sizes and charges are in the range of 90130 nm and ?30 mV respectively. The nanoparticles showed high encapsulation efficiency towards DOX as well as pH controlled release. This has significant anti-proliferative activity against MCF-7 breast cancer cells after irradiation at near infra-red (NIR) ranges were evaluated. This could have potential applications in photo-controlled smart DOX delivery system for cancer treatment. 2019 Elsevier B.V. Creator An entity primarily responsible for making the resource Bhatta A.; Krishnamoorthy G.; Marimuthu N.; Dihingia A.; Manna P.; Biswal H.T.; Das M.; Krishnamoorthy G. Source A related resource from which the described resource is derived International Journal of Biological Macromolecules, Vol-136, pp. 951-961. Publisher An entity responsible for making the resource available Elsevier B.V. Date A point or period of time associated with an event in the lifecycle of the resource 2019-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1016/j.ijbiomac.2019.06.127" target="_blank" rel="noreferrer noopener">https://doi.org/10.1016/j.ijbiomac.2019.06.127</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85067852785&amp;doi=10.1016%2Fj.ijbiomac.2019.06.127&amp;partnerID=40&amp;md5=83e625a928e1eb84fed43c2714c4d408" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85067852785&amp;doi=10.1016%2fj.ijbiomac.2019.06.127&amp;partnerID=40&amp;md5=83e625a928e1eb84fed43c2714c4d408</a> Rights Information about rights held in and over the resource Restricted Access Relation A related resource ISSN: 1418130; PubMed ID: 31226376; CODEN: IJBMD Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Article Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Bhatta A., Natural Products Chemistry Groups, Chemical Science &amp; Technology Division, CSIR-North East Institute of Science &amp; Technology (NEIST), Jorhat, 785 006, Assam, India; Krishnamoorthy G., Natural Products Chemistry Groups, Chemical Science &amp; Technology Division, CSIR-North East Institute of Science &amp; Technology (NEIST), Jorhat, 785 006, Assam, India; Marimuthu N., Department of Chemistry, CHRIST (Deemed to be University), Bengaluru, 560029, Karnataka, India; Dihingia A., Biotechnology Group, Biological Science &amp; Technology Division, CSIR-North East Institute of Science &amp; Technology (NEIST), Jorhat, 785 006, Assam, India; Manna P., Biotechnology Group, Biological Science &amp; Technology Division, CSIR-North East Institute of Science &amp; Technology (NEIST), Jorhat, 785 006, Assam, India; Biswal H.T., Department of Chemistry, Indian Institute of Technology Guwahati (IITG), Guwahati, 781 039, Assam, India; Das M., Department of Chemistry, Indian Institute of Technology Guwahati (IITG), Guwahati, 781 039, Assam, India; Krishnamoorthy G., Department of Chemistry, Indian Institute of Technology Guwahati (IITG), Guwahati, 781 039, Assam, India