Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Articles Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Evaluation of cytotoxicity and antioxidant properties of some Zingiberaceae plants Subject The topic of the resource 2,3,5-triphenyltetrazolium chloride; Cytotoxicity; Reactive oxygen species; Zingiberaceae Description An account of the resource Aim: Zingiberaceae family is widely distributed in the tropical realm of Asia. Considering its diverse applications as spices and therapeutics, the present study was undertaken to evaluate the cytotoxic and antioxidant effect of the ethanolic rhizome extracts of five plants, namely Alpinia galanga (L.) Willd., Alpinia zerumbet (Pers.) B.L. Burtt and R. M. Smith, Curcuma caesia Roxb., Zingiber officinale Rosc., and Zingiber zerumbet (L.) Smith on Allium cepa Linn. system. Materials and Methods: Cytotoxicity was evaluated by 2,3,5-triphenyltetrazolium chloride (TTC) and 2',7'-dichlorofluorescein diacetate (DCFDAH 2 ) assays. Further, in vitro DNA protection assay was performed to confirm the antioxidant potentials of the extracts. Characterization of phytochemicals was done by performing qualitative tests. Results and Discussion: TTC reduction assay revealed that the extracts (2.5, 5, and 10 g/ml) had no cytotoxic effect on A. cepa root cells. Roots treated with extracts (2.5 g/ml) were stained with reactive oxygen species-sensitive dye DCFDAH 2 and visualized under the fluorescence microscope. The result confirmed that the extracts did not exert any prooxidant effect. Further, the extracts established their substantial antioxidant potential by inhibiting oxidative DNA damage in an in vitro system. In addition, qualitative analysis showed that the rhizomes are rich in phytochemicals. Conclusion: From the current observations, it can be concluded that the selected herbs can be utilized safely for human consumption. 2019 BRNSS Publication Hub. All Rights Reserved. Creator An entity primarily responsible for making the resource Nag A.; Chakraborty M.; Banerjee R.; Mukherjee A. Source A related resource from which the described resource is derived International Journal of Green Pharmacy, Vol-12, No. 4, pp. S870-S875. Publisher An entity responsible for making the resource available BRNSS Publication Hub Date A point or period of time associated with an event in the lifecycle of the resource 2018-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.22377/ijgp.v12i04.2268" target="_blank" rel="noreferrer noopener">https://doi.org/10.22377/ijgp.v12i04.2268</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85063179009&amp;doi=10.22377%2Fijgp.v12i04.2268&amp;partnerID=40&amp;md5=160786d16739dc3b072196eee7dde1d6" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85063179009&amp;doi=10.22377%2fijgp.v12i04.2268&amp;partnerID=40&amp;md5=160786d16739dc3b072196eee7dde1d6</a> Rights Information about rights held in and over the resource All Open Access; Bronze Open Access Relation A related resource ISSN: 9738258 Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Article Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Nag A., Department of Life Sciences, CHRIST (Deemed to be University), Bengaluru, Karnataka, 560 029, India; Chakraborty M., Department of Botany, Cell Biology and Genetic Toxicology Laboratory, University of Calcutta, Kolkata, West Bengal, India; Banerjee R., Department of Botany, Cell Biology and Genetic Toxicology Laboratory, University of Calcutta, Kolkata, West Bengal, India; Mukherjee A., Department of Botany, Cell Biology and Genetic Toxicology Laboratory, University of Calcutta, Kolkata, West Bengal, India