ItemArticle

PEDOT decorated with PTIR nanoclusters on carbon fiber paper toward electrocatalytic reduction of a hypertensive drug olmesartan medoxomil

Title
PEDOT decorated with PTIR nanoclusters on carbon fiber paper toward electrocatalytic reduction of a hypertensive drug olmesartan medoxomil
Creator
Akshaya K.B.; Vinod T.P.; Nidhin M.; Varghese A.; George L.
Description
A facile electrochemical sensor was developed by electrochemical deposition of PtIr nanoparticles on poly(3,4ethylenedioxythiophene) (PEDOT) modified carbon fiber paper electrode (CFP). The modified electrodes were characterized by Field emission scanning electron microscopy (FESEM) with energy-dispersive X-ray spectroscopy (EDS), X-ray diffraction (XRD), RAMAN spectroscopy, Fourier transform infrared spectroscopy (FTIR) and electroanalytical techniques. PtIr-PEDOT modified CFP electrode was used successfully in the determination of an anti-hypertensive prodrug Olmesartan medoxomil (OM) at femtomolar (fM) level for the first time. Under optimal conditions, the prepared electrochemical sensor has shown broad linear range between 0.001 pM and 0.220 pM and superior detection limit of 3.42 fM was observed based on Differential pulse voltammetric (DPV) study. In addition, the designed electrochemical sensor was successfully demonstrated as a novel platform in the electrochemical determination of OM in human urine and pharmaceutical samples. 2018 The Electrochemical Society.
Source
Journal of the Electrochemical Society, Vol-165, No. 13, pp. B582-B595.
Date
2018-01-01
Publisher
Electrochemical Society Inc.
Coverage
Akshaya K.B., Department of Chemistry, CHRIST (Deemed to be University), Bengaluru, 560 029, India; Vinod T.P., Department of Chemistry, CHRIST (Deemed to be University), Bengaluru, 560 029, India; Nidhin M., Department of Chemistry, CHRIST (Deemed to be University), Bengaluru, 560 029, India; Varghese A., Department of Chemistry, CHRIST (Deemed to be University), Bengaluru, 560 029, India; George L., Department of Chemistry, CHRIST (Deemed to be University), Bengaluru, 560 029, India
Rights
Restricted Access
Relation
ISSN: 134651; CODEN: JESOA
Format
Online
Language
English
Type
Article

Collection

Articles

Citation

Akshaya K.B.; Vinod T.P.; Nidhin M.; Varghese A.; George L., “PEDOT decorated with PTIR nanoclusters on carbon fiber paper toward electrocatalytic reduction of a hypertensive drug olmesartan medoxomil,” CHRIST (Deemed To Be University) Institutional Repository, accessed February 24, 2025, https://archives.christuniversity.in/items/show/16965.

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