New constituents triterpene ester and sugar derivatives from Panax ginseng Meyer and their evaluation of antioxidant activities
- Title
- New constituents triterpene ester and sugar derivatives from Panax ginseng Meyer and their evaluation of antioxidant activities
- Creator
- Chung I.-M.; Siddiqui N.A.; Kim S.H.; Nagella P.; Khan A.A.; Ali M.; Ahmad A.
- Description
- Panax ginseng C. A. Meyer (Araliaceae), is a well-known herb and used in the old established system of Oriental remedy, especially in Japan, China and Korea. Four new compounds characterized as (cis)- 7?,11?,19,21-tetra-O-decanoyl-18, 22?-dihydroxy-dammar-1-en-3-one (1), 3?,4?,12?-trihydroxystigmast-5-en-21-yl octadecan-9?,12?-dienoate (2), dammar-12, 24-dien-3?, 6?, 15?-triol-3?-D-arabinopyranosyl-6?-L-arabinopyranoside (3) and dammar-24-en-3?, 6?, 16?, 20?-tetraol-3?-D-arabinopyranosyl-6?-D-arabinopyranoside (4) were isolated and established from the ethyl acetate and butanol extracts of the roots of P. ginseng. Their structures were established on the basis of spectral data and chemical reactions. Natural compounds indicative a great reservoir of materials and compounds with evolved biological activity, including antioxidant. Compounds 14 were investigated in vitro for antioxidant potential using ferric reducing antioxidant power (FRAP), the Nitric oxide (NO) scavenging activity, reducing power, phosphomolybdenum and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging actions, and the decision showed the compounds 3and 4 have probablyessential antioxidant properties than the compounds 1and 2 presented weak activity. 2016 The Authors
- Source
- Saudi Pharmaceutical Journal, Vol-25, No. 5, pp. 801-812.
- Date
- 2017-01-01
- Publisher
- Elsevier B.V.
- Subject
- Antioxidant activities; Araliaceae; New constituents; Panax ginseng
- Coverage
- Chung I.-M., Department of Applied Bioscience, College of Life and Environmental Sciences, Konkuk University, Seoul, 143-701, South Korea; Siddiqui N.A., Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh 11451, P.O. Box 2457, Saudi Arabia; Kim S.H., Department of Applied Bioscience, College of Life and Environmental Sciences, Konkuk University, Seoul, 143-701, South Korea; Nagella P., Department of Botany, Christ University, Bengaluru, 560029, India; Khan A.A., Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh, 11451, Saudi Arabia; Ali M., Department of Pharmacognosy and Phytochemistry, Hamdard University, New Delhi, 110062, India; Ahmad A., Process Chemistry and Technology Department, Central Institute of Medicinal and Aromatic Plants, Lucknow, 226015, India, Previously in Department of Applied Bioscience, Konkuk University, Seoul, 143-701, South Korea
- Rights
- All Open Access; Gold Open Access; Green Open Access
- Relation
- ISSN: 13190164; CODEN: SPJOE
- Format
- Online
- Language
- English
- Type
- Article
Collection
Citation
Chung I.-M.; Siddiqui N.A.; Kim S.H.; Nagella P.; Khan A.A.; Ali M.; Ahmad A., “New constituents triterpene ester and sugar derivatives from Panax ginseng Meyer and their evaluation of antioxidant activities,” CHRIST (Deemed To Be University) Institutional Repository, accessed February 23, 2025, https://archives.christuniversity.in/items/show/17122.