Ultrasound assisted Friedel-Crafts acylation of aromatics using ferric sulphate as catalyst
- Title
- Ultrasound assisted Friedel-Crafts acylation of aromatics using ferric sulphate as catalyst
- Creator
- Sridharan A.; Gopalakrishnan G.
- Description
- The use of ultrasound in the acylation reactions of various aromatics and polyaromatics with different acyl chlorides, in the presence of catalytic amount of ferric sulphate at room temperature, gives good yields of the respective ketones with a short reaction time. A facile and simple synthesis of various aromatic ketones using Friedel-Crafts acylation has been established from the corresponding acid chlorides and aromatic or polyaromatic compounds, respectively under mild reaction conditions with shorter reaction times (30-45 min) and in reasonable yields. This method offers the advantage of low cost and ease of purification of the products because of the small amount of ferric sulphate used in these reactions.
- Source
- Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, Vol-50, No. 9, pp. 1192-1195.
- Date
- 2011-01-01
- Subject
- Acylation; Aromatics; Catalyst; Reaction time; Ultrasound; Yield
- Coverage
- Sridharan A., Department of Chemistry, Christ University, Bangalore 560 029, Hosur Road, India; Gopalakrishnan G., Schering Plough Singapore Ltd., Singapore 638408, 50 Tuas West Drive, Singapore
- Rights
- Restricted Access
- Relation
- ISSN: 3764699; CODEN: IJSBD
- Format
- Online
- Language
- English
- Type
- Article
Collection
Citation
Sridharan A.; Gopalakrishnan G., “Ultrasound assisted Friedel-Crafts acylation of aromatics using ferric sulphate as catalyst,” CHRIST (Deemed To Be University) Institutional Repository, accessed February 24, 2025, https://archives.christuniversity.in/items/show/17373.