Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Book Chapter Book Chapter Faculty Publications- Book Chapter Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Production of bioactive compounds from cell and organ cultures of Centella asiatica Subject The topic of the resource bioreactor; Centella asiatica; centellosides; elicitation; plant tissue culture Description An account of the resource Centella asiatica, commonly known as mandukaparni, has garnered recognition for its efficacy in addressing a spectrum of health concerns. Its diverse pharmacological properties encompass roles in treating neuro-related issues, gastrointestinal problems, and cardiovascular conditions. Furthermore, it exhibits multifaceted therapeutic effects, including antioxidant, antidiabetic, wound healing, skin protective, and anti-osteoporotic properties. This herbaceous plant is rich in bioactive compounds such as centellosides (triterpene saponins) including madecassoside, madecassic acid, asiatic acid, and asiaticoside. These compounds, crucial for their pharmacological potential, are biosynthetically produced through the mevalonate and methylerythritol phosphate pathways. However, the challenge lies in the production of these important secondary metabolites, given the adverse impact on the availability of mandukaparni due to increasing demand. To address this concern, this chapter emphasizes the biotechnological interventions for the production of bioactive phytochemicals. These include plant tissue culture techniques, such as cell and organ cultures, along with elicitation strategies, genetic engineering approaches, and bioreactor-scale production. These methods aim to enhance the sustainable production of centellosides, providing valuable insights for researchers and paving the way for future opportunities in the field of plant-based therapeutics. 2024 Elsevier Inc. All rights are reserved including those for text and data mining AI training and similar technologies. Creator An entity primarily responsible for making the resource Vasantha V.L.; Sudheer W.N.; Al-Khayri J.M.; Jain S.M.; Nagella P. Source A related resource from which the described resource is derived Biotechnological Production of Bioactive Phytochemicals of Medicinal Value: a Comprehensive Treatise, pp. 585-603. Publisher An entity responsible for making the resource available Elsevier Date A point or period of time associated with an event in the lifecycle of the resource 2024-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1016/B978-0-443-21818-7.00015-0" target="_blank" rel="noreferrer noopener">https://doi.org/10.1016/B978-0-443-21818-7.00015-0</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85202884357&amp;doi=10.1016%2FB978-0-443-21818-7.00015-0&amp;partnerID=40&amp;md5=d59c902796919b8a37b92af0c8b9f078" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85202884357&amp;doi=10.1016%2fB978-0-443-21818-7.00015-0&amp;partnerID=40&amp;md5=d59c902796919b8a37b92af0c8b9f078</a> Rights Information about rights held in and over the resource Restricted Access Relation A related resource ISBN: 978-044321818-7; 978-044321819-4 Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Book chapter Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Vasantha V.L., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bangalore, India; Sudheer W.N., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bangalore, India; Al-Khayri J.M., Department of Agricultural Biotechnology, College of Agriculture and Food Sciences, King Faisal University, Al-Ahsa, Saudi Arabia; Jain S.M., Department of Agricultural Sciences, University of Helsinki, Helsinki, Finland; Nagella P., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bangalore, India