Nanobiosensors: A Promising Tool for the Determination of Pathogenic Bacteria
Electrochemical nanobiosensors; Limit of detection; Linear range; Nanobiosensors; Optical nano biosensing; Pathogenic bacterial detection; Point-of-care detection
Pathogenic bacterial detection is a significant concern for the well-being of all human beings. These tiny microbes are capable of causing numerous diseases, which can be nipped in the bud through proper monitoring and controlling at the early stages itself. Some common pathogenic bacteria include Mycobacterium tuberculosis, Bacillus anthracis, Streptococcus pneumoniae, Escherichia coli, Salmonella spp., etc. These microbes contaminate air, food, and water through different modes of transmission. The classical methods used for the identification of these bacteria are time-killing and backbreaking. Rapid pathogenic bacteria determination became possible through the intervention of biosensors. Biosensors are further modified with nanoparticles to build nanobiosensors that are tenfold efficient in bacterial detection. The optical and electrochemical nanobiosensors provide hassle-free detection of pathogenic bacteria, and pointof- care detection is also possible. This book chapter aims to give a brief idea about nanobiosensors starting from the principle to the advantages and disadvantages of bacterial detection. Relevant works of literature on different methods to detect bacteria, types of nanobiosensors, and their efficacy in pathogenic bacterial detection portray the current stand and the need for more innovations in the area of nanobiosensors. The Editor(s) (if applicable) and The Author(s), under exclusive licence to Springer Nature Singapore Pte Ltd. 2022.
Agnihotri A.S.; George A.M.C.; Marimuthu N.
Nanotechnology for Infectious Diseases, pp. 475-495.
Agnihotri A.S., Department of Chemistry, CHRIST (Deemed to be University), Bengaluru, India; George A.M.C., Department of Chemistry, CHRIST (Deemed to be University), Bengaluru, India; Marimuthu N., Department of Chemistry, CHRIST (Deemed to be University), Bengaluru, India