Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Book Chapter Book Chapter Faculty Publications- Book Chapter Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource In Vitro Production of Tocopherols Subject The topic of the resource Biological activity; Biosynthesis; Elicitation strategies; Metabolic engineering; Plant cell and organ culture; Tocopherol Description An account of the resource Tocopherols are an essential dietary nutrient for mammals and photosynthetic products produced by green plants. Tocopherols commonly referred to as vitamin E exist in four forms (?-, ?-, ?-, and ?-tocopherol). Synthetic ?-tocopherol is a mixture of eight racemic forms and is less effective than natural tocopherol, thus the demand for plant-derived tocopherols is high. Tocopherols are lipophilic antioxidant and extensively used as therapeutic agents such as anti-inflammatory, anti-infection, anticancer, immune-stimulant, and nephro-protectant. They are also used as food additives and nutraceuticals. Plant cell and tissue culture is one of the promising techniques for mass production of tocopherols to meet the commercial demand. Optimizing physical and chemical factors for in vitro culture system has resulted in better accumulation of the product. Moreover, using bioreactors, precursor feeding, elicitation, biotransformation, and metabolic engineering approaches have resulted in enhanced yield of tocopherols from in vitro cultures. The present chapter deals with various important aspects of tocopherol in vitro production such as biosynthesis of tocopherol with special emphasis on key enzymes involved in the pathway whose modulation in expression can increase the yield of the product. Topics discussed include production of tocopherol from callus, cell and organ culture, metabolic engineering for mass production, different methods employed for extraction and quantification of tocopherols, and their biological activities and commercial applications. The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2022. Creator An entity primarily responsible for making the resource Lakshmaiah V.V.; Joseph B.V.; Bhaskar R.; Ulhas R.S.; Al-Khayri J.M.; Nagella P. Source A related resource from which the described resource is derived Nutraceuticals Production from Plant Cell Factory, pp. 287-319. Publisher An entity responsible for making the resource available Springer Nature Date A point or period of time associated with an event in the lifecycle of the resource 2022-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1007/978-981-16-8858-4_12" target="_blank" rel="noreferrer noopener">https://doi.org/10.1007/978-981-16-8858-4_12</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85160113306&amp;doi=10.1007%2F978-981-16-8858-4_12&amp;partnerID=40&amp;md5=8045cc47499d53a31bce269ed402091e" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85160113306&amp;doi=10.1007%2f978-981-16-8858-4_12&amp;partnerID=40&amp;md5=8045cc47499d53a31bce269ed402091e</a> Rights Information about rights held in and over the resource Restricted Access Relation A related resource ISBN: 978-981168858-4; 978-981168857-7 Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Book chapter Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Lakshmaiah V.V., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bengaluru, India; Joseph B.V., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bengaluru, India; Bhaskar R., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bengaluru, India; Ulhas R.S., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bengaluru, India; Al-Khayri J.M., Department of Agricultural Biotechnology, College of Agriculture and Food Sciences, King Faisal University, Al-Ahsa, Saudi Arabia; Nagella P., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bengaluru, India