Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Book Chapter Book Chapter Faculty Publications- Book Chapter Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource GutBrain Axis: Role in Hunger and Satiety Subject The topic of the resource Hunger; Metabolic disorder; Microbiome; Obesity; Probiotics; Satiety Description An account of the resource The human gastrointestinal tract consists of nearly 100 trillion microorganisms, referred as gut microbiota or gut microbiome. The microbial colonization in the human gut begins at the time of birth and its colonization increases with age which is influenced by factors like age, diet, and antibiotic treatment. Gut microbiota is believed to play a major role in human health as well as various physiological activities like metabolism, nutrition, physiology, etc. Imbalance of the normal gut microbiota has been linked with gastrointestinal conditions such as inflammatory bowel disease (IBD), irritable bowel syndrome (IBS) as well as wider systemic manifestations of disease such as obesity, type 2 diabetes, and atopy. Gutbrain axis, a two-way (bi-directional) connection and communication between the gut and the brain has potentially huge influence over our health which integrates neural, hormonal, and immunological signaling between the gut and the brain. There is growing evidence on the influence of gastrointestinal (GI) microbiota that modulates appetite, feeding, and metabolism as well as regulates the mechanisms of digestion. Gut hormones like Ghrelin, Cholecystokinin (CCK), Pancreatic Polypeptide (PP), Peptide YY (PYY), Glucagon-Like Peptide 1 (GLP-1), Oxyntomodulin (OXM), Glucagon, Gastric Inhibitory Polypeptide (GIP), and Amylin have been identified in the gastrointestinal system which have a fundamental role in coordinating digestive process within the gastrointestinal system, thus regulating feeding behavior and energy balance. Studies have indicated that the modulation in gut microbiota regulates the production of ghrelin and PYY in overweight and obese patients and helps in promoting weight loss and improves glucose regulation. Considering the importance of the role of gut microbiota on hunger and satiety, this chapter was written where we have discussed the gutbrain axis and its role in hunger and satiety. Further, mechanism of appetite regulation by gut microbiota and their role in obesity control have also been discussed. Finally, future perspectives on application of gut microbiota as potential probiotic solutions for obesity and related metabolic disorders will be discussed. Springer Nature Singapore Pte Ltd. 2022. Creator An entity primarily responsible for making the resource Krishna K.V.; Malviya S.; Bhattacharyya D.; Malaviya A. Source A related resource from which the described resource is derived Probiotic Research in Therapeutics: Volume 5: Metabolic Diseases and Gut Bacteria, Vol-5, pp. 1-27. Publisher An entity responsible for making the resource available Springer Nature Date A point or period of time associated with an event in the lifecycle of the resource 2022-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1007/978-981-16-8444-9_1" target="_blank" rel="noreferrer noopener">https://doi.org/10.1007/978-981-16-8444-9_1</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85137349020&amp;doi=10.1007%2F978-981-16-8444-9_1&amp;partnerID=40&amp;md5=690a90fa0f1a42d2e106ecdeb3b338b7" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85137349020&amp;doi=10.1007%2f978-981-16-8444-9_1&amp;partnerID=40&amp;md5=690a90fa0f1a42d2e106ecdeb3b338b7</a> Rights Information about rights held in and over the resource Restricted Access Relation A related resource ISBN: 978-981168444-9; 978-981168443-2 Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Book chapter Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Krishna K.V., Applied and Industrial Biotechnology Laboratory (AIBL), Department of Life Sciences, CHRIST (Deemed to be University), Bengaluru, India; Malviya S., National Centre for Biological Sciences (NCBS), TATA Institute of Fundamental Research, GKVK Campus, Bengaluru, India; Bhattacharyya D., Applied and Industrial Biotechnology Laboratory (AIBL), Department of Life Sciences, CHRIST (Deemed to be University), Bengaluru, India; Malaviya A., Applied and Industrial Biotechnology Laboratory (AIBL), Department of Life Sciences, CHRIST (Deemed to be University), Bengaluru, India