In vitro cytotoxicity studies of Ga2O3 microstructures on L929 and MCF-7 cell lines using MTT assay

Title

In vitro cytotoxicity studies of Ga2O3 microstructures on L929 and MCF-7 cell lines using MTT assay

Creator

Raphael R.; Aswathy W.F.; Anila E.I.

Description

Considering the therapeutic promise of gallium, its compounds are currently undergoing preclinical and clinical development in different phases. In this work, Ga2O3 microstructures were synthesized using hydrothermal methods followed by calcination at (Formula presented.). For structural and morphological analysis, x-ray diffraction spectrum and field emission scanning electron microscopy images were used. In vitro cytotoxicity and in vitro anticancer effects of the sample were determined by cell culture imaging and MTT assay method. The studies were carried out on L929 and MCF-7 cell lines. The present study reveals the possibility of extending Ga2O3 for anticancer drug applications. The Author(s), under exclusive licence to The Materials Research Society 2024.

Source

MRS Communications, Vol-14, No. 6, pp. 1359-1363.

Date

2024-01-01

Publisher

Springer Nature

Subject

Biomedical; Powder; Scanning electron microscopy (SEM); Toxicity; X-ray diffraction (XRD)

Coverage

Raphael R., Optoelectronic and Nanomaterials Research Laboratory, Union Christian College, Kerala, Aluva, 683102, India; Aswathy W.F., Christ (Deemed to Be University), Karnataka, Bangalore, 560029, India; Anila E.I., Optoelectronic and Nanomaterials Research Laboratory, Union Christian College, Kerala, Aluva, 683102, India, Christ (Deemed to Be University), Karnataka, Bangalore, 560029, India

Rights

Restricted Access

Relation

ISSN: 21596859

Format

Online

Language

English

Type

Letter

Identifier

https://doi.org/10.1557/s43579-024-00647-z

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