Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Reviews Review Faculty Publications- Reviews Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource An extensive review on transition metal catalyzed indole C[sbnd]H activation: Catalyst selection and mechanistic insights Subject The topic of the resource Antiviral drugs; Catalyst; CH activation of indoles; Iridium; Palladium; Rhodium; Ruthenium and manganese Description An account of the resource The present review article explores the expansive synthetic methodologies facilitated by C[sbnd]H activation of indoles using transition metal catalysts. The strategic utilization of catalysts such as palladium, rhodium, iridium, ruthenium, and manganese has revolutionized organic synthesis by enabling selective alkynylation, acylation, and annulation reactions. These transformations are pivotal in pharmaceuticals, particularly in the synthesis of antihistamines and potential antiviral drugs against SARS-CoV-2. Additionally, these catalysts play a crucial role in perfumery and other chemical industries, enhancing the efficiency and precision of compound synthesis. The choice of transition metal catalysts is informed by their affordability and compatibility with both traditional analytical methods and innovative techniques like microwave synthesis and LED irradiation. Furthermore, this review underscores the interdisciplinary impact of transition metal-catalyzed C[sbnd]H activation on indoles, highlighting its significance in advancing both fundamental organic chemistry and applied sciences essential for modern technological advancements and drug discovery efforts. 2024 The Author(s) Creator An entity primarily responsible for making the resource Ann Mary C.J.; Vasudevan D.; Nagarajan P.; Suhas S.; Vijayan A.; Radhakrishnan K.V.; Sudhakar Y.N. Source A related resource from which the described resource is derived Polyhedron, Vol-264 Publisher An entity responsible for making the resource available Elsevier Ltd Date A point or period of time associated with an event in the lifecycle of the resource 2024-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1016/j.poly.2024.117260" target="_blank" rel="noreferrer noopener">https://doi.org/10.1016/j.poly.2024.117260</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85207075188&amp;doi=10.1016%2Fj.poly.2024.117260&amp;partnerID=40&amp;md5=7efa5f7135ccf6e7488423cd0e34de08" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85207075188&amp;doi=10.1016%2fj.poly.2024.117260&amp;partnerID=40&amp;md5=7efa5f7135ccf6e7488423cd0e34de08</a> Rights Information about rights held in and over the resource All Open Access; Hybrid Gold Open Access Relation A related resource ISSN: 2775387; CODEN: PLYHD Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Review Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Ann Mary C.J., Department of Chemistry, Christ University, Hosur Road, Karnataka, Bengaluru, 560029, India; Vasudevan D., Department of Chemistry, Christ University, Hosur Road, Karnataka, Bengaluru, 560029, India; Nagarajan P., Department of Chemistry, Christ University, Hosur Road, Karnataka, Bengaluru, 560029, India; Suhas S., Department of Chemistry, Christ University, Hosur Road, Karnataka, Bengaluru, 560029, India; Vijayan A., Department of Chemistry, Christ University, Hosur Road, Karnataka, Bengaluru, 560029, India; Radhakrishnan K.V., CSIR- National Institute for Interdisciplinary Science and Technology, Industrial Estate P. O., Thiruvananthapuram, 695019, India; Sudhakar Y.N., Department of Chemistry, Manipal Institute of Technology, Manipal Academy of Higher Education, Karnataka, Manipal, 576104, India