Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Reviews Review Faculty Publications- Reviews Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Epigenetic Mechanisms Induced by Mycobacterium tuberculosis to Promote Its Survival in the Host Subject The topic of the resource apoptosis; autophagy; epigenetics; macrophage polarization; miRNA modification; tuberculosis Description An account of the resource Tuberculosis caused by the obligate intracellular pathogen, Mycobacterium tuberculosis, is one among the prime causes of death worldwide. An urgent remedy against tuberculosis is of paramount importance in the current scenario. However, the complex nature of this appalling disease contributes to the limitations of existing medications. The quest for better treatment approaches is driving the research in the field of host epigenomics forward in context with tuberculosis. The interplay between various host epigenetic factors and the pathogen is under investigation. A comprehensive understanding of how Mycobacterium tuberculosis orchestrates such epigenetic factors and favors its survival within the host is in increasing demand. The modifications beneficial to the pathogen are reversible and possess the potential to be better targets for various therapeutic approaches. The mechanisms, including histone modifications, DNA methylation, and miRNA modification, are being explored for their impact on pathogenesis. In this article, we are deciphering the role of mycobacterial epigenetic regulators on various strategies like cytokine expression, macrophage polarization, autophagy, and apoptosis, along with a glimpse of the potential of host-directed therapies. 2024 by the authors. Creator An entity primarily responsible for making the resource Thomas S.S.; Abhinand K.; Menon A.M.; Nair B.G.; Kumar G.B.; Arun K.B.; Edison L.K.; Madhavan A. Source A related resource from which the described resource is derived International Journal of Molecular Sciences, Vol-25, No. 21 Publisher An entity responsible for making the resource available Multidisciplinary Digital Publishing Institute (MDPI) Date A point or period of time associated with an event in the lifecycle of the resource 2024-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.3390/ijms252111801" target="_blank" rel="noreferrer noopener">https://doi.org/10.3390/ijms252111801</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85208533155&amp;doi=10.3390%2Fijms252111801&amp;partnerID=40&amp;md5=467d51e3c619f66be865735de524bb2a" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85208533155&amp;doi=10.3390%2fijms252111801&amp;partnerID=40&amp;md5=467d51e3c619f66be865735de524bb2a</a> Rights Information about rights held in and over the resource All Open Access; Gold Open Access Relation A related resource ISSN: 16616596; PubMed ID: 39519352 Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Review Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Thomas S.S., School of Biotechnology, Amrita Vishwa Vidyapeetham, AmritapuriKerala, Kollam, 690525, India; Abhinand K., School of Biotechnology, Amrita Vishwa Vidyapeetham, AmritapuriKerala, Kollam, 690525, India; Menon A.M., School of Biotechnology, Amrita Vishwa Vidyapeetham, AmritapuriKerala, Kollam, 690525, India; Nair B.G., School of Biotechnology, Amrita Vishwa Vidyapeetham, AmritapuriKerala, Kollam, 690525, India; Kumar G.B., School of Biotechnology, Amrita Vishwa Vidyapeetham, AmritapuriKerala, Kollam, 690525, India; Arun K.B., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bangalore, 560029, India; Edison L.K., Department of Comparative, Diagnostic, and Population Medicine, College of Veterinary Medicine, University of Florida, Gainesville, 32610, FL, United States; Madhavan A., School of Biotechnology, Amrita Vishwa Vidyapeetham, AmritapuriKerala, Kollam, 690525, India