Enzyme based bioelectrocatalysis over laccase immobilized poly-thiophene supported carbon fiber paper for the oxidation of D-ribofuranose to D-ribonolactone /
Title
Enzyme based bioelectrocatalysis over laccase immobilized poly-thiophene supported carbon fiber paper for the oxidation of D-ribofuranose to D-ribonolactone /
Subject
Chemistry
Description
Molecular Catalysis, Vol.524, ISSN No: 2468-8231.
A modified electrode based on laccase immobilized poly-thiophene-3-carboxylic acid supported on carbon fiber paper was developed for the electrocatalytic oxidation of D-ribofuranose to otherwise difficult-to-access D-ribonolactone, a precursor for C-nucleoside based drug like Remdesivir. The electrochemical oxidation of D-ribofuranose was achieved by the TEMPO-mediated electrochemical process. The experimental parameters were optimized and validated using Design of Experiment (DoE) statistical tool indicating the concentration of TEMPO and stirring as important parameters in bulk electrolysis.
A modified electrode based on laccase immobilized poly-thiophene-3-carboxylic acid supported on carbon fiber paper was developed for the electrocatalytic oxidation of D-ribofuranose to otherwise difficult-to-access D-ribonolactone, a precursor for C-nucleoside based drug like Remdesivir. The electrochemical oxidation of D-ribofuranose was achieved by the TEMPO-mediated electrochemical process. The experimental parameters were optimized and validated using Design of Experiment (DoE) statistical tool indicating the concentration of TEMPO and stirring as important parameters in bulk electrolysis.
Creator
Thadathil, Ditto Abraham., Varghese, Anitha., Ahamed, Chekrain Valappil Shihas., Krishnakumar, K A., Varma, Sanjay Suresh., Lankalapalli, Ravi S., Radhakrishnan, Kokkuvayil Vasu.
Publisher
ScienceDirect
Date
2022
Language
English
Type
Research Publication
Collection
Citation
Thadathil, Ditto Abraham., Varghese, Anitha., Ahamed, Chekrain Valappil Shihas., Krishnakumar, K A., Varma, Sanjay Suresh., Lankalapalli, Ravi S., Radhakrishnan, Kokkuvayil Vasu., “Enzyme based bioelectrocatalysis over laccase immobilized poly-thiophene supported carbon fiber paper for the oxidation of D-ribofuranose to D-ribonolactone /,” CHRIST (Deemed To Be University) Institutional Repository, accessed December 3, 2024, https://archives.christuniversity.in/items/show/2128.