Enzyme based bioelectrocatalysis over laccase immobilized poly-thiophene supported carbon fiber paper for the oxidation of D-ribofuranose to D-ribonolactone /
- Title
- Enzyme based bioelectrocatalysis over laccase immobilized poly-thiophene supported carbon fiber paper for the oxidation of D-ribofuranose to D-ribonolactone /
- Creator
- Thadathil, Ditto Abraham., Varghese, Anitha., Ahamed, Chekrain Valappil Shihas., Krishnakumar, K A., Varma, Sanjay Suresh., Lankalapalli, Ravi S., Radhakrishnan, Kokkuvayil Vasu.
- Description
- Molecular Catalysis, Vol.524, ISSN No: 2468-8231.
A modified electrode based on laccase immobilized poly-thiophene-3-carboxylic acid supported on carbon fiber paper was developed for the electrocatalytic oxidation of D-ribofuranose to otherwise difficult-to-access D-ribonolactone, a precursor for C-nucleoside based drug like Remdesivir. The electrochemical oxidation of D-ribofuranose was achieved by the TEMPO-mediated electrochemical process. The experimental parameters were optimized and validated using Design of Experiment (DoE) statistical tool indicating the concentration of TEMPO and stirring as important parameters in bulk electrolysis. - Date
- 2022-05-13
- Publisher
- ScienceDirect
- Subject
- Chemistry
- Language
- English
- Type
- Research Publication
Files
Collection
Citation
Thadathil, Ditto Abraham., Varghese, Anitha., Ahamed, Chekrain Valappil Shihas., Krishnakumar, K A., Varma, Sanjay Suresh., Lankalapalli, Ravi S., Radhakrishnan, Kokkuvayil Vasu., “Enzyme based bioelectrocatalysis over laccase immobilized poly-thiophene supported carbon fiber paper for the oxidation of D-ribofuranose to D-ribonolactone /,” CHRIST (Deemed To Be University) Institutional Repository, accessed February 13, 2025, https://archives.christuniversity.in/items/show/2128.