Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Reviews Review Faculty Publications- Reviews Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource A rapid investigation of near-infrared (NIR) fluorescent switch-on probes for detection and in cellulo tracking of G-quadruplex and double-stranded DNA Description An account of the resource This review provides a comprehensive overview of the recent advancements in Near Infrared (NIR) fluorescence switch-on probes designed for the detection and in cellulo tracking of G-quadruplex and double-stranded DNA (dsDNA). G-quadruplexes, non-canonical DNA structures, play pivotal roles in regulating various biological processes, making them critical targets for therapeutic and diagnostic applications. The unique properties of NIR fluorescence probes, such as deep tissue penetration, minimal photodamage, and low autofluorescence background, offer significant advantages for bioimaging. We critically analyze the design strategies, photophysical properties, and binding mechanisms of various NIR fluorescence switch-on probes. Additionally, we discuss their efficacy and specificity in identifying G-quadruplexes and dsDNA within cellular environments. Key challenges and future directions for improving the sensitivity, selectivity, and biocompatibility of these probes are also highlighted. This review aims to underscore the potential of NIR fluorescence probes in advancing our understanding of DNA dynamics and their applications in biomedical research. 2024 The Royal Society of Chemistry. Creator An entity primarily responsible for making the resource Shinziya H.; Menon R.S.; Das A.K. Source A related resource from which the described resource is derived RSC Advances, Vol-14, No. 42, pp. 30631-30646. Publisher An entity responsible for making the resource available Royal Society of Chemistry Date A point or period of time associated with an event in the lifecycle of the resource 2024-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1039/d4ra06207h" target="_blank" rel="noreferrer noopener">https://doi.org/10.1039/d4ra06207h</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85205460531&amp;doi=10.1039%2Fd4ra06207h&amp;partnerID=40&amp;md5=3c777d933a574f7f7f95bafabb28cf75" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85205460531&amp;doi=10.1039%2fd4ra06207h&amp;partnerID=40&amp;md5=3c777d933a574f7f7f95bafabb28cf75</a> Rights Information about rights held in and over the resource All Open Access; Gold Open Access Relation A related resource ISSN: 20462069; CODEN: RSCAC Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Review Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Shinziya H., Department of Chemistry, Christ University, Hosur Road, Karnataka, Bangalore, 560029, India; Menon R.S., Department of Chemistry, Christ University, Hosur Road, Karnataka, Bangalore, 560029, India; Das A.K., Department of Chemistry, Christ University, Hosur Road, Karnataka, Bangalore, 560029, India