Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Reviews Review Faculty Publications- Reviews Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Recent advances in polyethylene glycol as a dual-functional agent in heterocycle synthesis: Solvent and catalyst Subject The topic of the resource catalysis; green solvent; polyethylene glycol-400; recyclability; review Description An account of the resource Reactant solubility, which dictates achievable concentrations, and the stability of reaction intermediates (excited states), solvents modulate the potential energy landscape and influence reaction rates. Consequently, solvent selection is pivotal in optimizing process productivity, economic feasibility, and environmental footprint. At present, organic synthesis pivots around the idea of sustainability. In particular, PEG-400, a popular solvent and phase transfer catalyst, is considered greener as it can be reused several times without significant loss in its catalytic activity, which checks the box regarding sustainability. This review highlights the emerging potential of Polyethylene Glycol 400 (PEG-400) as a dual-threat agent in sustainable organic synthesis. We explore its efficacy as a catalyst, promoting various reactions under mild conditions and often eliminating the need for traditional metal catalysts. Additionally, PEG-400's role as a green solvent is addressed, emphasizing its biodegradability, low toxicity, and ability to facilitate reactions without hazardous Volatile Organic Compounds (VOCs). The review examines recent research on PEG-400 mediated reactions, showcasing its effectiveness in diverse transformations, thus exploring the potential of PEG 400 as a facilitator for heterocycle synthesis in both multicomponent reactions and stepwise approaches. It identifies exciting research directions that promise to expand the boundaries of polymer-based solvents in heterocyclic chemistry. 2024 The Author(s). Polymers for Advanced Technologies published by John Wiley &amp; Sons Ltd. Creator An entity primarily responsible for making the resource Servesh A.; Lokesh Kumar S.; Govindaraju S.; Tabassum S.; Raj Prasad J.; Kumar N.; Ramaraj S.G. Source A related resource from which the described resource is derived Polymers for Advanced Technologies, Vol-35, No. 6 Publisher An entity responsible for making the resource available John Wiley and Sons Ltd Date A point or period of time associated with an event in the lifecycle of the resource 2024-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1002/pat.6433" target="_blank" rel="noreferrer noopener">https://doi.org/10.1002/pat.6433</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85194710532&amp;doi=10.1002%2Fpat.6433&amp;partnerID=40&amp;md5=a7c163b0fa83f18ae8d27e35849482f5" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85194710532&amp;doi=10.1002%2fpat.6433&amp;partnerID=40&amp;md5=a7c163b0fa83f18ae8d27e35849482f5</a> Rights Information about rights held in and over the resource All Open Access; Hybrid Gold Open Access Relation A related resource ISSN: 10427147 Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Review Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Servesh A., Department of Chemistry, Christ University, Karnataka, Bengaluru, India; Lokesh Kumar S., Department of Chemistry, Christ University, Karnataka, Bengaluru, India; Govindaraju S., Department of Sciences &amp; Humanities, Christ University, Karnataka, Bengaluru, India; Tabassum S., Department of Chemistry, Surana College, Karnataka, Bengaluru, India; Raj Prasad J., Department of Civil Engineering, College of Engineering and Technology, SRM Institute of Science and Technology, Tamilnadu, Katankulathur, India; Kumar N., Department of Electronic &amp; Communication Engineering, Graphics Era Deemed to be University, Uttarakhand, Dehradun, India; Ramaraj S.G., Department of Bioengineering, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan, Department of Materials Physics, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences (SIMTS), Tamilnadu, Chennai, India