Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Reviews Review Faculty Publications- Reviews Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bioreactor configurations for adventitious root culture: recent advances toward the commercial production of specialized metabolites Subject The topic of the resource Adventitious roots; airlift bioreactors; bubble column bioreactors; cell cultures; organ cultures; scale-up process; specialized metabolites; stirred tank bioreactors Description An account of the resource In vitro plant cell and organ cultures are appealing alternatives to traditional methods of producing valuable specialized metabolites for use as: pharmaceuticals, food additives, cosmetics, perfumes, and agricultural chemicals. Cell cultures have been adopted for the production of specialized metabolites in certain plants. However, in certain other systems, adventitious roots are superior to cell suspension cultures as they are organized structures that accumulate high levels of specialized metabolites. The cultivation of adventitious roots has been investigated in various bioreactor systems, including: mechanically agitated, pneumatically agitated, and modified bioreactors. The main relevance and importance of this work are to develop a long-lasting industrial biotechnological technology as well as to improve the synthesis of these metabolites from the plant in vitro systems. These challenges are exacerbated by: the peculiarities of plant cell metabolism, the complexity of specialized metabolite pathways, the proper selection of bioreactor systems, and bioprocess optimization. This reviews major objective is to analyze several bioreactor types for the development of adventitious roots, as well as the advantages and disadvantages of each type of bioreactor, and to describe the strategies used to increase the synthesis of specialized metabolites. This review also emphasizes current advancements in the field, and successful instances of scaled-up cultures and the generation of specialized metabolites for commercial purposes are also covered. 2023 Informa UK Limited, trading as Taylor &amp; Francis Group. Creator An entity primarily responsible for making the resource Murthy H.N.; Joseph K.S.; Paek K.Y.; Park S.Y. Source A related resource from which the described resource is derived Critical Reviews in Biotechnology, Vol-44, No. 5, pp. 837-859. Publisher An entity responsible for making the resource available Taylor and Francis Ltd. Date A point or period of time associated with an event in the lifecycle of the resource 2024-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1080/07388551.2023.2233690" target="_blank" rel="noreferrer noopener">https://doi.org/10.1080/07388551.2023.2233690</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85173039657&amp;doi=10.1080%2F07388551.2023.2233690&amp;partnerID=40&amp;md5=db5cd2520face04ff4dd1c870145505c" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85173039657&amp;doi=10.1080%2f07388551.2023.2233690&amp;partnerID=40&amp;md5=db5cd2520face04ff4dd1c870145505c</a> Rights Information about rights held in and over the resource Restricted Access Relation A related resource ISSN: 7388551; PubMed ID: 37500186; CODEN: CRBTE; LS; 2023-2024; Vol-1; 0460-0483 Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Review Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Murthy H.N., Department of Botany, Karnatak University, Dharwad, India, Department of Horticultural Science, Chungbuk National University, Cheongju, South Korea; Joseph K.S., Department of Life Sciences, CHRIST (Deemed to be University), Bengaluru, India; Paek K.Y., Department of Horticultural Science, Chungbuk National University, Cheongju, South Korea; Park S.Y., Department of Horticultural Science, Chungbuk National University, Cheongju, South Korea