Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Reviews Review Faculty Publications- Reviews Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bioactive compounds from Cordyceps and their therapeutic potential Subject The topic of the resource Bioactive compounds; C. militaris; Cordycepin; Cordyceps sinesis; Himalayan viagra; Keeda Jadi Description An account of the resource The Clavicipitaceae familys largest and most diverse genus is Cordyceps. They are most abundant and diverse in humid temperate and tropical forests and have a wide distribution in: Europe, North America, and East and Southeast Asian countries, particularly: Bhutan, China, Japan, Nepal, Korea, Thailand, Vietnam, Tibet, and the Himalayan region of India, and Sikkim. It is a well-known parasitic fungus that feeds on insects and other arthropods belonging to 10 different orders. Over 200 bioactive metabolites, that include: nucleotides and nucleosides, polysaccharides, proteins, polypeptides, amino acids, sterols, and fatty acids, among others have been extracted from Cordyceps spp. demonstrating the phytochemical richness of this genus. These components have been associated with a variety of pharmacological effects, including: anti-microbial, anti-apoptotic, anti-cancer, anti-inflammatory, antioxidant, and immunomodulatory activities. In this paper, the bioactivity of various classes of metabolites produced by Cordyceps spp., and their therapeutic properties have been reviewed in an attempt to update the existing literature. Furthermore, one of its nucleoside and a key bioactive compound, cordycepin has been critically elaborated with regard to its biosynthesis pathway and the recently proposed protector-protmechanism as well as various biological and pharmacological effects, such as: suppression of purine and nucleic acid biosynthesis, induction of apoptosis, and cell cycle regulation with their mechanism of action. This review provides current knowledge on the bioactive potential of Cordyceps spp. 2023 Informa UK Limited, trading as Taylor &amp; Francis Group. Creator An entity primarily responsible for making the resource Krishna K.V.; Ulhas R.S.; Malaviya A. Source A related resource from which the described resource is derived Critical Reviews in Biotechnology, Vol-44, No. 5, pp. 753-773. Publisher An entity responsible for making the resource available Taylor and Francis Ltd. Date A point or period of time associated with an event in the lifecycle of the resource 2024-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1080/07388551.2023.2231139" target="_blank" rel="noreferrer noopener">https://doi.org/10.1080/07388551.2023.2231139</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85175117662&amp;doi=10.1080%2F07388551.2023.2231139&amp;partnerID=40&amp;md5=d09f776a98d9858272a9a97385e751e1" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85175117662&amp;doi=10.1080%2f07388551.2023.2231139&amp;partnerID=40&amp;md5=d09f776a98d9858272a9a97385e751e1</a> Rights Information about rights held in and over the resource Restricted Access Relation A related resource ISSN: 7388551; PubMed ID: 37518188; CODEN: CRBTE Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Review Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Krishna K.V., Applied and Industrial Biotechnology Laboratory, Christ (Deemed-to-be University), Karnataka, Bangalore, India; Ulhas R.S., Institute of Biochemistry and Biophysics, Faculty of Life Sciences, University of Jena (Friedrich-Schiller-Universit Jena), Jena, Germany; Malaviya A., Applied and Industrial Biotechnology Laboratory, Christ (Deemed-to-be University), Karnataka, Bangalore, India, Division of Life Sciences, Gyeongsang National University, Gyeongsangnam-do, South Korea, QuaLife Biotech Pvt Ltd, Bangalore, India