Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Reviews Review Faculty Publications- Reviews Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Cadmium as an Endocrine Disruptor That Hinders the Reproductive and Developmental Pathways in Freshwater Fish: A Review Subject The topic of the resource cadmium; endocrine disruptor; freshwater fish; HPG axis; metallothionein; reproductive and developmental impairments Description An account of the resource Cadmium (Cd) is a non-essential element with sub-lethal effects even at low concentrations. The persistent nature of Cd and its tendency to bioaccumulate eventually create harmful effects on water biota, including fish. Cd affects various aspects of hormonal action in fish since it bioaccumulates in the endocrine system and hinders the synthesis, secretion, and metabolic activity of hormones, causing severe damage along the hypothalamuspituitarygonadal axis. Linking reproductive and developmental impairments in fish with ecologically relevant concentrations of individual metals can be challenging due to the complexity of aquatic ecosystems. This review deliberated the significant and novel trends of toxicological difficulties and approaches, including elucidating environmental sources bioavailability and Cd-induced toxic effects in freshwater fish. Both acute and chronic exposure to Cd can cause a range of adverse effects, such as growth inhibition, impaired reproductive capacity, endocrine disruption, and developmental abnormalities in freshwater fish, as evidenced by the present review. These investigations support the concept of Cd as a naturally available pollutant that causes irreversible damage in fish. These findings will help to understand the etiology of environmental circumstances that pose substantial dangers to fish health and are also crucial for preventing and treating exposure-related reproductive disturbances in freshwater fish due to environmental pollution. 2023 by the authors. Creator An entity primarily responsible for making the resource Vinanthi Rajalakshmi K.S.; Liu W.-C.; Balamuralikrishnan B.; Meyyazhagan A.; Sattanathan G.; Pappuswamy M.; Joseph K.S.; Paari K.A.; Lee J.-W. Source A related resource from which the described resource is derived Fishes, Vol-8, No. 12 Publisher An entity responsible for making the resource available Multidisciplinary Digital Publishing Institute (MDPI) Date A point or period of time associated with an event in the lifecycle of the resource 2023-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.3390/fishes8120589" target="_blank" rel="noreferrer noopener">https://doi.org/10.3390/fishes8120589</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85180652629&amp;doi=10.3390%2Ffishes8120589&amp;partnerID=40&amp;md5=413e10286fa839ac6745ca35e6a66604" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85180652629&amp;doi=10.3390%2ffishes8120589&amp;partnerID=40&amp;md5=413e10286fa839ac6745ca35e6a66604</a> Rights Information about rights held in and over the resource All Open Access; Gold Open Access Relation A related resource ISSN: 24103888; LS; 2023-2024; Vol-1; 0500-0520 Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Review Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Vinanthi Rajalakshmi K.S., Department of Life Sciences, School of Sciences, Christ University, Karnataka, Bangalore, 560029, India; Liu W.-C., Department of Animal Science, College of Coastal Agricultural Sciences, Guangdong Ocean University, Zhanjiang, 524088, China; Balamuralikrishnan B., Department of Food Science and Biotechnology, College of Life Science, Sejong University, Seoul, 05006, South Korea; Meyyazhagan A., Department of Life Sciences, School of Sciences, Christ University, Karnataka, Bangalore, 560029, India; Sattanathan G., Department of Zoology, St. Joseph University, Nagaland, Chumukedima, 797115, India; Pappuswamy M., Department of Life Sciences, School of Sciences, Christ University, Karnataka, Bangalore, 560029, India; Joseph K.S., Department of Life Sciences, School of Sciences, Christ University, Karnataka, Bangalore, 560029, India; Paari K.A., Department of Life Sciences, School of Sciences, Christ University, Karnataka, Bangalore, 560029, India; Lee J.-W., Department of Integrative Biological Sciences and Industry, Sejong University, Seoul, 05006, South Korea