Multicomponent Synthesis Strategies, Catalytic Activities, and Potential Therapeutic Applications of Pyranocoumarins: A Comprehensive Review
- Title
- Multicomponent Synthesis Strategies, Catalytic Activities, and Potential Therapeutic Applications of Pyranocoumarins: A Comprehensive Review
- Creator
- Jayalakshmi M.; Joy F.; Nizam A.; Naidu Krishna S.B.
- Description
- Fused coumarins, because of their remarkable biological and therapeutic properties, particularly pyranocoumarins, have caught the interest of synthetic organic chemists, leading to the development of more efficient and environmentally friendly protocols for synthesizing pyranocoumarin derivatives. These compounds are the most promising heterocycles discovered in both natural and synthetic sources, with anti-inflammatory, anti-HIV, antitubercular, antihyperglycemic, and antibacterial properties. This review employed the leading scientific databases Scopus, Web of Science, Google Scholar, and PubMed up to the end of 2022, as well as the combining terms pyranocoumarins, synthesis, isolation, structural elucidation, and biological activity. Among the catalysts employed, acidic magnetic nanocatalysts, transition metal catalysts, and carbon-based catalysts have all demonstrated improved reaction yields and facilitated reactions under milder conditions. Herein, the present review discusses the various multicomponent synthetic strategies for pyranocoumarins catalyzed by transition metal-based catalysts, transition metal-based nanocatalysts, transition metal-free catalysts, carbon-based nanocatalysts, and their potential pharmacological activities. 2023 The Authors. Chemistry & Biodiversity published by Wiley-VHCA AG, Zurich, Switzerland.
- Source
- Chemistry and Biodiversity, Vol-20, No. 10
- Date
- 2023-01-01
- Publisher
- John Wiley and Sons Inc
- Subject
- carbon-based nanocatalyst; organocatalyst; pyranocoumarins; transition metal-based catalyst; transition metal-based nanocatalyst
- Coverage
- Jayalakshmi M., Department of Chemistry, CHRIST (Deemed to be University), Karnataka, Bangalore, 560029, India; Joy F., Department of Chemistry, CHRIST (Deemed to be University), Karnataka, Bangalore, 560029, India; Nizam A., Department of Chemistry, CHRIST (Deemed to be University), Karnataka, Bangalore, 560029, India; Naidu Krishna S.B., Institute for Water and Wastewater Technology, Durban University of Technology, Durban, 4000, South Africa, Department of Biomedical and Clinical Technology, Durban University of Technology, Durban, 4000, South Africa
- Rights
- All Open Access; Hybrid Gold Open Access
- Relation
- ISSN: 16121872; PubMed ID: 37702294; CODEN: CBHIA
- Format
- Online
- Language
- English
- Type
- Review
Collection
Citation
Jayalakshmi M.; Joy F.; Nizam A.; Naidu Krishna S.B., “Multicomponent Synthesis Strategies, Catalytic Activities, and Potential Therapeutic Applications of Pyranocoumarins: A Comprehensive Review,” CHRIST (Deemed To Be University) Institutional Repository, accessed February 24, 2025, https://archives.christuniversity.in/items/show/21397.