Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Reviews Review Faculty Publications- Reviews Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource The crux of bioactive metabolites in endophytic and thermophilic fungi and their proximal prospects in biotechnological and industrial domains Subject The topic of the resource Biomedical; Bioprospecting; Endophytic fungi; Enzymes; Secondary metabolites; Thermophilic fungi Description An account of the resource Fungi are ubiquitous in distribution and are found in grasses to hot springs. Their mode of nutrition provides sustenance for living and propagation. Ironically, varied fungal species have developed customized strategies for protection and survival by producing diverse secondary metabolites. The review aimed to project the contrasting potential features of the endophytic and thermophilic fungi groups. The metabolites and the enzymes of endophytic and thermophilic fungi served as the backbone to thrive and adapt within-host and in extreme conditions like higher pH, heat, and salinity, respectively. Identification, knowledge of their biochemistry and pathway, exploration, production, and utilization of these bioactive molecules in various commercial, industrial, and pharmaceutical domains were briefly discussed. The uniqueness of endophytes includes stress management and improved biomass production of the host, green fuel production, omnipresence, selected triple-symbiosis with the virus, synthesis of polyketides, and other active metabolites are widely used in biomedical applications and agriculture management. This review attempted to limelight the specific applications of thermophilic fungal metabolites and the roles of thermo-stable enzymes in bioprospecting. Moreover, probing the metabolites of thermophiles rendered novel antibiotic compounds, which were proven effective against multi-drug resistant bacteria and harboured the potential to curtail infectious diseases. 2022 Elsevier Ltd Creator An entity primarily responsible for making the resource Pushparaj K.; Meyyazhagan A.; Bhotla H.K.; Arumugam V.A.; Pappuswamy M.; Vadivalagan C.; Hakeem K.R.; Balasubramanian B.; Liu W.; Mousavi Khaneghah A. Source A related resource from which the described resource is derived Toxicon, Vol-223 Publisher An entity responsible for making the resource available Elsevier Ltd Date A point or period of time associated with an event in the lifecycle of the resource 2023-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1016/j.toxicon.2022.107007" target="_blank" rel="noreferrer noopener">https://doi.org/10.1016/j.toxicon.2022.107007</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85144812706&amp;doi=10.1016%2Fj.toxicon.2022.107007&amp;partnerID=40&amp;md5=1072e2948afd415813caee56e3c71248" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85144812706&amp;doi=10.1016%2fj.toxicon.2022.107007&amp;partnerID=40&amp;md5=1072e2948afd415813caee56e3c71248</a> Rights Information about rights held in and over the resource Restricted Access Relation A related resource ISSN: 410101; PubMed ID: 36563862; CODEN: TOXIA Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Review Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Pushparaj K., Department of Zoology, School of Biosciences, Avinashilingam Institute for Home Science and Higher Education for Women, Tamil Nadu, Coimbatore, 641 043, India; Meyyazhagan A., Department of Life Science, CHRIST (Deemed to Be University), Karnataka, Bengaluru, 560076, India; Bhotla H.K., Department of Life Science, CHRIST (Deemed to Be University), Karnataka, Bengaluru, 560076, India; Arumugam V.A., Department of Human Genetics and Molecular Biology, Bharathiar University, Tamil Nadu, Coimbatore, 641 046, India; Pappuswamy M., Department of Life Science, CHRIST (Deemed to Be University), Karnataka, Bengaluru, 560076, India; Vadivalagan C., Department of Cosmeceutics, China Medical University, Taichung City, 406040, Taiwan; Hakeem K.R., Department of Biological Sciences, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah, 21589, Saudi Arabia; Balasubramanian B., Department of Food Science and Biotechnology, College of Life Science, Sejong University, Seoul, 05006, South Korea; Liu W., Department of Animal Science, College of Coastal Agricultural Sciences, Guangdong Ocean University, Zhanjiang, 524088, China; Mousavi Khaneghah A., Department of Fruit and Vegetable Product Technology, Prof. Wac?awD?browski Institute of Agricultural and Food Biotechnology State Research Institute, 36 Rakowiecka St., Warsaw, 02-532, Poland, Department of Technology of Chemistry, Azerbaijan State Oil and Industry University, Baku, Azerbaijan