Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Reviews Review Faculty Publications- Reviews Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource In vitro Analytical Techniques as Screening Tools to investigate the Metal chelate-DNA interactions Subject The topic of the resource Deoxyribose nucleic acid; Fluorescence spectroscopy; Metal -DNA complex; Molecular docking; UV-Vis spectroscopy Description An account of the resource Deoxyribose nucleic acid (DNA) is found to be the most efficient pharmacological target of many synthetic molecules which are deemed as potential drugs with clinical applications. DNA binding agents are known to regulate several cell functions (gene expression and replication) by adopting various protocols which include the annihilation of the cell membrane, interruption in protein synthesis, and irreversible binding to cell receptors. Recently, several studies have explored fundamental aspects of drug-DNA interactions, providing new insights into the driving forces that render the formation of the drug-DNA complex. In order to study and understand these biologically important reaction mechanisms, several screening tools have been devised and the specificity of drug molecules binding to DNA were studied in detail. This review will discuss the utilization of various analytical tools which include UV-vis spectroscopy, fluorescence spectroscopy, circular dichroism, viscosity measurement, Raman spectroscopy, cyclic voltammetry, and DNA fragmentation assay used for studying drug binding mode and the mechanism involved. 2023 Wiley-VCH GmbH. Creator An entity primarily responsible for making the resource Varghese N.; Jose J.R.; Krishna P.M.; Philip D.; Joy F.; Vinod T.P.; Prathapachandra Kurup M.R.; Nair Y. Source A related resource from which the described resource is derived ChemistrySelect, Vol-8, No. 5 Publisher An entity responsible for making the resource available John Wiley and Sons Inc Date A point or period of time associated with an event in the lifecycle of the resource 2023-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1002/slct.202203615" target="_blank" rel="noreferrer noopener">https://doi.org/10.1002/slct.202203615</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85147379568&amp;doi=10.1002%2Fslct.202203615&amp;partnerID=40&amp;md5=fac960e4933ae3624ba8375cfdbf05c7" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85147379568&amp;doi=10.1002%2fslct.202203615&amp;partnerID=40&amp;md5=fac960e4933ae3624ba8375cfdbf05c7</a> Rights Information about rights held in and over the resource Restricted Access Relation A related resource ISSN: 23656549 Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Review Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Varghese N., Department of Chemistry, CHRIST (Deemed to be University), Hosur Road, Karnataka, Bengaluru, 560 029, India; Jose J.R., Department of Chemistry, CHRIST (Deemed to be University), Hosur Road, Karnataka, Bengaluru, 560 029, India; Krishna P.M., Department of Chemistry, Ramaiah institute of technology, MSRIT Post, M S Ramaiah Nagar, Karnataka, Bengaluru, 560054, India; Philip D., Department of Chemistry, CHRIST (Deemed to be University), Hosur Road, Karnataka, Bengaluru, 560 029, India; Joy F., Department of Chemistry, CHRIST (Deemed to be University), Hosur Road, Karnataka, Bengaluru, 560 029, India; Vinod T.P., Department of Chemistry, CHRIST (Deemed to be University), Hosur Road, Karnataka, Bengaluru, 560 029, India; Prathapachandra Kurup M.R., Department of Applied Chemistry, Cochin university of science and technology, Kochi, 682022, India; Nair Y., Department of Chemistry, CHRIST (Deemed to be University), Hosur Road, Karnataka, Bengaluru, 560 029, India