Anthraquinone Production from Cell and Organ Cultures of Rubia Species: An Overview

Title

Anthraquinone Production from Cell and Organ Cultures of Rubia Species: An Overview

Creator

Murthy H.N.; Joseph K.S.; Paek K.Y.; Park S.Y.

Description

The Rubia genus includes major groups of medicinal plants such as Rubia cordifolia, Rubia tinctorum, and Rubia akane. They contain anthraquinones (AQs), particularly alizarin and purpurin, which have pharmacological effects that are anti-inflammatory, antioxidant, anticancer, hemostatic, antibacterial, and more. Alizarin and purpurin have been utilized as natural dyes for cotton, silk, and wool fabrics since the dawn of time. These substances have been used in the cosmetics and food industries to color products. The amount of AQs in different Rubia species is minimal. In order to produce these compounds, researchers have established cell and organ cultures. Investigations have been conducted into numerous chemical and physical parameters that affect the biomass and accumulation of secondary metabolites in a cell, callus, hairy root, and adventitious root suspension cultures. This article offers numerous techniques and approaches used to produce biomass and secondary metabolites from the Rubia species. Additionally, it has been emphasized that cells can be grown in bioreactor cultures to produce AQs. 2022 by the authors.

Source

Metabolites, Vol-13, No. 1

Date

2023-01-01

Publisher

MDPI

Subject

alizarin; anthraquinones; bioreactors; cell cultures; dyes; purpurin; secondary metabolites

Coverage

Murthy H.N., Department of Botany, Karnatak University, Dharwad, 580003, India, Department of Horticultural Science, Chungbuk National University, Cheongju, 28644, South Korea; Joseph K.S., Department of Life Sciences, CHRIST (Deemed to be University), Bengaluru, 560029, India; Paek K.Y., Department of Horticultural Science, Chungbuk National University, Cheongju, 28644, South Korea; Park S.Y., Department of Horticultural Science, Chungbuk National University, Cheongju, 28644, South Korea

Rights

All Open Access; Gold Open Access; Green Open Access

Relation

ISSN: 22181989

Format

Online

Language

English

Type

Review

Identifier

https://doi.org/10.3390/metabo13010039

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85146766097&doi=10.3390%2fmetabo13010039&partnerID=40&md5=aebd23b5a2eee79d12132e17a29aa7fd