Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Reviews Review Faculty Publications- Reviews Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource A comprehensive review on tissue culture studies and secondary metabolite production in Bacopa monnieri L. Pennell: a nootropic plant Subject The topic of the resource Agrobacterium rhizogenes; Bacopa monnieri; bacoside A; multiple shoot culture; plant cell culture; secondary metabolites Description An account of the resource Bacopa monnieri L. Pennell, commonly known as Brahmi, is an important medicinal plant that belongs to the family Plantaginaceae. Brahmi is rich in innumerable bioactive secondary metabolites, especially bacosides that can be employed to reduce many health issues. This plant is used as a neuro-tonic and treatment for mental health, depression, and cognitive performance. Brahmi is also known for its antioxidant, anti-inflammatory, and anti-hepatotoxic activities. There is a huge demand for its raw materials, particularly for the extraction of bioactive molecules. The conventional mode of propagation could not meet the required commercial demand. To overcome this, biotechnological approaches, such as plant tissue culture techniques have been established for the production of important secondary metabolites through various culture techniques, such as callus and cell suspension cultures and organ cultures, to allow for rapid propagation and conservation of medicinally important plants with increased production of bioactive compounds. It has been found that a bioreactor-based technology can also enhance the multiplication rate of cell and organ cultures for commercial propagation of medicinally important bioactive molecules. The present review focuses on the propagation and production of bacoside A by cell and organ cultures of Bacopa monnieri, a nootropic plant. The review also focuses on the biosynthesis of bacoside A, different elicitation strategies, and the over-expression of genes for the production of bacoside-A. It also identifies research gaps that need to be addressed in future studies for the sustainable production of bioactive molecules from B. monnieri. 2022 Informa UK Limited, trading as Taylor &amp; Francis Group. Creator An entity primarily responsible for making the resource Sudheer W.N.; Thiruvengadam M.; Nagella P. Source A related resource from which the described resource is derived Critical Reviews in Biotechnology, Vol-43, No. 6, pp. 956-970. Publisher An entity responsible for making the resource available Taylor and Francis Ltd. Date A point or period of time associated with an event in the lifecycle of the resource 2023-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1080/07388551.2022.2085544" target="_blank" rel="noreferrer noopener">https://doi.org/10.1080/07388551.2022.2085544</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85134013205&amp;doi=10.1080%2F07388551.2022.2085544&amp;partnerID=40&amp;md5=7c429a374049d7e26057e507e68447cb" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85134013205&amp;doi=10.1080%2f07388551.2022.2085544&amp;partnerID=40&amp;md5=7c429a374049d7e26057e507e68447cb</a> Rights Information about rights held in and over the resource Restricted Access Relation A related resource ISSN: 7388551; PubMed ID: 35819370; CODEN: CRBTE Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Review Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Sudheer W.N., Department of Life Sciences, CHRIST (Deemed to be University), Bengaluru, India; Thiruvengadam M., Department of Crop Science, College of Sanghuh Life Science, Konkuk University, Seoul, South Korea; Nagella P., Department of Life Sciences, CHRIST (Deemed to be University), Bengaluru, India