Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Reviews Review Faculty Publications- Reviews Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Betulinic acid: A natural promising anticancer drug, current situation, and future perspectives Subject The topic of the resource anticancer; apoptosis; betulin; betulinic acid; cytotoxicity; hydrosolubility; pharmacokinetics Description An account of the resource Natural products serve as the single most productive source for the discovery of drugs and pharmaceutical leads. Among the various chemicals derived from microbes, plants, and animals, phytochemicals have emerged as potential candidates for the development of anticancer drugs due to their structural diversities, complexities, and pleiotropic effects. Herein, we discuss betulinic acid (BA), a ubiquitously distributed lupane structured pentacyclic triterpenoid, scrutinized as a promising natural agent for the prevention, suppression, and management of various human malignancies. Ease of availability, common occurrences, cell-specific cytotoxicity, and astonishing selectivity are the important factors that contribute to the development of BA as an anticancer agent. The current review delineates the mechanistic framework of BA-mediated cancer suppression through the modulation of multiple signaling pathways and also summarizes the key outcomes of BA in preclinical investigations. 2022 Wiley Periodicals LLC. Creator An entity primarily responsible for making the resource Aswathy M.; Vijayan A.; Daimary U.D.; Girisa S.; Radhakrishnan K.V.; Kunnumakkara A.B. Source A related resource from which the described resource is derived Journal of Biochemical and Molecular Toxicology, Vol-36, No. 12 Publisher An entity responsible for making the resource available John Wiley and Sons Inc Date A point or period of time associated with an event in the lifecycle of the resource 2022-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1002/jbt.23206" target="_blank" rel="noreferrer noopener">https://doi.org/10.1002/jbt.23206</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85138238643&amp;doi=10.1002%2Fjbt.23206&amp;partnerID=40&amp;md5=b37a1b268f04deab1c2115fc233820c9" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85138238643&amp;doi=10.1002%2fjbt.23206&amp;partnerID=40&amp;md5=b37a1b268f04deab1c2115fc233820c9</a> Rights Information about rights held in and over the resource Restricted Access Relation A related resource ISSN: 10956670; PubMed ID: 36124371; CODEN: JBMTF Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Review Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Aswathy M., Chemical Sciences and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology (CSIR-NIIST), Thiruvananthapuram, India, Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India; Vijayan A., Department of Chemistry, CHRIST (Deemed to be University), Bangalore, India; Daimary U.D., Cancer Biology Laboratory, Department of Biosciences and Bioengineering,Indian Institute of Technology, Assam, Guwahati, India; Girisa S., Cancer Biology Laboratory, Department of Biosciences and Bioengineering,Indian Institute of Technology, Assam, Guwahati, India; Radhakrishnan K.V., Chemical Sciences and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology (CSIR-NIIST), Thiruvananthapuram, India; Kunnumakkara A.B., Cancer Biology Laboratory, Department of Biosciences and Bioengineering,Indian Institute of Technology, Assam, Guwahati, India