Synthetic Approaches to Diospongins: A Two Decade Journey
- Title
- Synthetic Approaches to Diospongins: A Two Decade Journey
- Creator
- Tadiparthi K.; Chatterjee S.
- Description
- Tetrahydropyran units having multiple stereogenic centers serve as excellent building blocks for various active pharmaceutical ingredients (APIs). In particular, the presence of the unique molecular architecture of the trisubstituted tetrahydropyran (THP) unit in diospongins enhances their biological activity due to multiple stereogenic centers and has attracted attention from the synthetic community over the last two decades. In this review, we discuss synthetic approaches to chiral and racemic forms of diospongins during the period 2006 2020 in chronological order. 2022 by the authors.
- Source
- SynOpen, Vol-6, No. 3, pp. 141-157.
- Date
- 2022-01-01
- Publisher
- Georg Thieme Verlag
- Subject
- asymmetric allylation; cross-metathesis; diarylheptanoids; diospongins; enzyme resolution; hetero-Diels-Alder reaction; oxa-Michael addition; Prins cyclization; tetrahydropyran
- Coverage
- Tadiparthi K., Department of Chemistry, CHRIST (Deemed to Be University), Hosur Road, Bangalore, 560029, India; Chatterjee S., Department of Chemistry, CHRIST (Deemed to Be University), Hosur Road, Bangalore, 560029, India
- Rights
- All Open Access; Gold Open Access
- Relation
- ISSN: 25099396
- Format
- Online
- Language
- English
- Type
- Review
Collection
Citation
Tadiparthi K.; Chatterjee S., “Synthetic Approaches to Diospongins: A Two Decade Journey,” CHRIST (Deemed To Be University) Institutional Repository, accessed February 24, 2025, https://archives.christuniversity.in/items/show/21510.