Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Reviews Review Faculty Publications- Reviews Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Fungal Mushrooms: A Natural Compound With Therapeutic Applications Subject The topic of the resource antiviral; cardioprotective; immune boosters; immunomodulation; Medicinal mushrooms; radical scavenging Description An account of the resource Fungi are extremely diverse in terms of morphology, ecology, metabolism, and phylogeny. Approximately, 130 medicinal activities like antitumor, immunomodulation, antioxidant, radical scavenging, cardioprotective and antiviral actions are assumed to be produced by the various varieties of medicinal mushrooms. The polysaccharides, present in mushrooms like ?-glucans, micronutrients, antioxidants like glycoproteins, triterpenoids, flavonoids, and ergosterols can help establish natural resistance against infections and toxins. Clinical trials have been performed on mushrooms like Agaricus blazei Murrill Kyowa for their anticancer effect, A. blazei Murrill for its antihypertensive and cardioprotective effects, and some other mushrooms had also been evaluated for their neurological effects. The human evaluation dose studies had been also performed and the toxicity dose was evaluated from the literature for number of mushrooms. All the mushrooms were found to be safe at a dose of 2000mg/kg but some with mild side effects. The safety and therapeutic effectiveness of the fungal mushrooms had shifted the interest of biotechnologists toward fungal nanobiotechnology as the drug delivery system due to the vast advantages of nanotechnology systems. In complement to the vital nutritional significance of medicinal mushrooms, numerous species have been identified as sources of bioactive chemicals. Moreover, there are unanswered queries regarding its safety, efficacy, critical issues that affect the future mushroom medicine development, that could jeopardize its usage in the twenty-first century. Copyright 2022 Chugh, Mittal, MP, Arora, Bhattacharya, Chopra, Cavalu and Gautam. Creator An entity primarily responsible for making the resource Chugh R.M.; Mittal P.; MP N.; Arora T.; Bhattacharya T.; Chopra H.; Cavalu S.; Gautam R.K. Source A related resource from which the described resource is derived Frontiers in Pharmacology, Vol-13 Publisher An entity responsible for making the resource available Frontiers Media S.A. Date A point or period of time associated with an event in the lifecycle of the resource 2022-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.3389/fphar.2022.925387" target="_blank" rel="noreferrer noopener">https://doi.org/10.3389/fphar.2022.925387</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85134960878&amp;doi=10.3389%2Ffphar.2022.925387&amp;partnerID=40&amp;md5=d47c15439e028aed96718eff5b15ec85" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85134960878&amp;doi=10.3389%2ffphar.2022.925387&amp;partnerID=40&amp;md5=d47c15439e028aed96718eff5b15ec85</a> Rights Information about rights held in and over the resource All Open Access; Gold Open Access; Green Open Access Relation A related resource ISSN: 16639812 Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Review Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Chugh R.M., Department of Radiation Oncology, University of Kansas Medical Center, Kansas, KS, United States; Mittal P., School of Pharmaceutical Sciences, RIMT University, Punjab, Mandi Gobindgarh, India; MP N., CHRIST (Deemed to be University), Bangalore, India; Arora T., Department of Radiation Oncology, University of Kansas Medical Center, Kansas, KS, United States; Bhattacharya T., Innovation, Incubation and Industry (i-cube) Laboratory, Techno India NJR Institute of Technology, Udaipur, India, College of Chemistry and Chemical Engineering, Hubei University, Hubei, China; Chopra H., Chitkara College of Pharmacy, Chitkara University, Rajpura, India; Cavalu S., Faculty of Medicine and Pharmacy, University of Oradea, Oradea, Romania; Gautam R.K., MM School of Pharmacy, MM University, Sadopur-Ambala, India