Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Reviews Review Faculty Publications- Reviews Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Advancement and Challenges of Biosensing Using Field Effect Transistors Subject The topic of the resource biosensors; Debye length; field effect transistors; functionalization; screening; sensitivity; specificity Description An account of the resource Field-effect transistors (FETs) have become eminent electronic devices for biosensing applications owing to their high sensitivity, faster response and availability of advanced fabrication techniques for their production. The device physics of this sensor is now well understood due to the emergence of several numerical modelling and simulation papers over the years. The pace of advancement along with the knowhow of theoretical concepts proved to be highly effective in detecting deadly pathogens, especially the SARS-CoV-2 spike protein of the coronavirus with the onset of the (coronavirus disease of 2019) COVID-19 pandemic. However, the advancement in the sensing system is also accompanied by various hurdles that degrade the performance. In this review, we have explored all these challenges and how these are tackled with innovative approaches, techniques and device modifications that have also raised the detection sensitivity and specificity. The functional materials of the device are also structurally modified towards improving the surface area and minimizing power dissipation for developing miniaturized microarrays applicable in ultra large scale integration (ULSI) technology. Several theoretical models and simulations have also been carried out in this domain which have given a deeper insight on the electron transport mechanism in these devices and provided the direction for optimizing performance. 2022 by the authors. Creator An entity primarily responsible for making the resource Thriveni G.; Ghosh K. Source A related resource from which the described resource is derived Biosensors, Vol-12, No. 8 Publisher An entity responsible for making the resource available MDPI Date A point or period of time associated with an event in the lifecycle of the resource 2022-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.3390/bios12080647" target="_blank" rel="noreferrer noopener">https://doi.org/10.3390/bios12080647</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85137127533&amp;doi=10.3390%2Fbios12080647&amp;partnerID=40&amp;md5=5e69c15cc53200417800b8335ce06662" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85137127533&amp;doi=10.3390%2fbios12080647&amp;partnerID=40&amp;md5=5e69c15cc53200417800b8335ce06662</a> Rights Information about rights held in and over the resource All Open Access; Gold Open Access; Green Open Access Relation A related resource ISSN: 20796374; PubMed ID: 36005043; CODEN: BISSE Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Review Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Thriveni G., Department of Electronics and Communication Engineering, School of Engineering and Technology, CHRIST (Deemed to be University), Mysore Road, Kumbalgodu, Bengaluru, 560074, India; Ghosh K., Centre for Nanoelectronics and VLSI Design, Vellore Institute of Technology, Vandalur Kelambakkam Road, Chennai, 600127, India, Vellore Institute of Technology, School of Electronics Engineering, Vandalur Kelambakkam Road, Chennai, 600119, India