Mucormycosis (black fungus) ensuing COVID-19 and comorbidity meets - Magnifying global pandemic grieve and catastrophe begins
- Title
- Mucormycosis (black fungus) ensuing COVID-19 and comorbidity meets - Magnifying global pandemic grieve and catastrophe begins
- Creator
- Pushparaj K.; Kuchi Bhotla H.; Arumugam V.A.; Pappusamy M.; Easwaran M.; Liu W.-C.; Issara U.; Rengasamy K.R.R.; Meyyazhagan A.; Balasubramanian B.
- Description
- Post COVID-19, mucormycosis occurred after the SARS-CoV-2 has rampaged the human population and is a scorching problem among the pandemic globally, particularly among Asian countries. Invasive mucormycosis has been extensively reported from mild to severe COVID-19 survivors. The robust predisposing factor seems to be uncontrolled diabetes mellitus, comorbidity and immunosuppression acquired through steroid therapy. The prime susceptive reason for the increase of mucormycosis cases is elevated iron levels in the serum of the COVID survivors. A panoramic understanding of the infection has been elucidated based on clinical manifestation, genetic and non- genetic mechanisms of steroid drug administration, biochemical pathways and immune modulated receptor associations. This review lime-lights and addresses the What, Why, How and When about the COVID-19 associated mucormycosis (CAM) in a comprehensive manner with a pure intention to bring about awareness to the common public as the cases are inevitably and exponentially increasing in India and global countries as well. The article also unearthed the pathogenesis of mucormycosis and its association with the COVID-19 sequela, the plausible routes of entry, diagnosis and counter remedies to keep the infection at bay. Cohorts of case reports were analysed to spotlight the link between the pandemic COVID-19 and the nightmare-mucormycosis. 2021 Elsevier B.V.
- Source
- Science of the Total Environment, Vol-805
- Date
- 2022-01-01
- Publisher
- Elsevier B.V.
- Subject
- Comorbidity; COVID-19 induced Mucormycosis; Dexamethasone; Diagnosis; Hyperglycemia; Ketosis; Secondary infections
- Coverage
- Pushparaj K., Department of Zoology, School of Biosciences, Avinashilingam Institute for Home Science and Higher Education for Women, Coimbatore, 641 043, Tamil Nadu, India; Kuchi Bhotla H., Department of Life Science, CHRIST (Deemed to be University), Bengaluru, 560076, Karnataka, India; Arumugam V.A., Department of Human Genetics and Molecular Biology, Bharathiar University, Coimbatore, 641 046, Tamil Nadu, India; Pappusamy M., Department of Life Science, CHRIST (Deemed to be University), Bengaluru, 560076, Karnataka, India; Easwaran M., International Centre for Genetic Engineering and Biotechnology, New Delhi, 110067, India; Liu W.-C., Department of Animal Science, College of Coastal Agricultural Sciences, Guangdong Ocean University, Zhanjiang, 524088, China; Issara U., Division of Food Science and Technology Management, Faculty of Science and Technology, Rajamangala University of Technology Thanyaburi, Pathum Thani, 12110, Thailand; Rengasamy K.R.R., Green Biotechnologies Research Centre of Excellence, University of Limpopo, Private Bag X1106, Polokwane, Sovenga, 0727, South Africa; Meyyazhagan A., Department of Life Science, CHRIST (Deemed to be University), Bengaluru, 560076, Karnataka, India; Balasubramanian B., Department of Food Science and Biotechnology, College of Life Science, Sejong University, Seoul, 05006, South Korea
- Rights
- All Open Access; Green Open Access
- Relation
- ISSN: 489697; PubMed ID: 34818767; CODEN: STEVA
- Format
- Online
- Language
- English
- Type
- Review
Collection
Citation
Pushparaj K.; Kuchi Bhotla H.; Arumugam V.A.; Pappusamy M.; Easwaran M.; Liu W.-C.; Issara U.; Rengasamy K.R.R.; Meyyazhagan A.; Balasubramanian B., “Mucormycosis (black fungus) ensuing COVID-19 and comorbidity meets - Magnifying global pandemic grieve and catastrophe begins,” CHRIST (Deemed To Be University) Institutional Repository, accessed February 24, 2025, https://archives.christuniversity.in/items/show/21544.