Dietary nutrients and their control of the redox bioenergetic networks as therapeutics in redox dysfunctions sustained pathologies
- Title
- Dietary nutrients and their control of the redox bioenergetic networks as therapeutics in redox dysfunctions sustained pathologies
- Creator
- Kuchi Bhotla H.; Meyyazhagan A.; Pappusamy M.; Park S.; Arumugam V.A.; Pushparaj K.; Rengasamy K.R.; Liu W.; Balasubramanian B.
- Description
- Electrons exchange amongst the chemical species in an organism is a pivotal concomitant activity carried out by individual cells for basic cellular processes and continuously contribute towards the maintenance of bioenergetic networks plus physiological attributes like cell growth, phenotypic differences and nutritional adaptations. Humans exchange matter and energy via complex connections of metabolic pathways (redox reactions) amongst cells being a thermodynamically open system. Usually, these reactions are the real lifeline and driving forces of health and disease in the living entity. Many shreds of evidence support the secondary role of reactive species in the cellular process of control apoptosis and proliferation. Disrupted redox mechanisms are seen in malaises, like degenerative and metabolic disorders, cancerous cells. This review targets the importance of redox reactions in the body's normal functioning and the effects of its alterations in cells to obtain a better understanding. Understanding the redox dynamics in a pathological state can provide an opportunity for cure or diagnosis at the earlier stage and serve as an essential biomarker to predict in advance to give personalized therapy. Understanding redox metabolism can also highlight the use of naturally available antioxidant in the form of diet. 2021 Elsevier Ltd
- Source
- Pharmacological Research, Vol-170
- Date
- 2021-01-01
- Publisher
- Academic Press
- Subject
- Micronutrients; Mitochondrion; Pathological condition; Reactive species; Reduction-oxidation; Thiol groups
- Coverage
- Kuchi Bhotla H., Department of Life Sciences, CHRIST (Deemed to be University), Bengaluru, 560029, Karnataka, India; Meyyazhagan A., Department of Life Sciences, CHRIST (Deemed to be University), Bengaluru, 560029, Karnataka, India; Pappusamy M., Department of Life Sciences, CHRIST (Deemed to be University), Bengaluru, 560029, Karnataka, India; Park S., Department of Food Science and Biotechnology, College of Life Science, Sejong University, Seoul, 05006, South Korea; Arumugam V.A., Medical Genetics and Epigenetics Laboratory, Department of Human Genetics and Molecular Biology, Bharathiar University, Coimbatore, 641046, Tamil Nadu, India; Pushparaj K., Department of Zoology, School of Biosciences, Avinashilingam Institute for Home Science and Higher Education for Women, Coimbatore, 641 043, Tamil Nadu, India; Rengasamy K.R., Green Biotechnologies Research Centre of Excellence, University of Limpopo, Private Bag X1106, Sovenga, Polokwane, 0727, South Africa; Liu W., Department of Animal Science, College of Coastal Agricultural Sciences, Guangdong Ocean University, Zhanjiang, 524088, China; Balasubramanian B., Department of Food Science and Biotechnology, College of Life Science, Sejong University, Seoul, 05006, South Korea
- Rights
- Restricted Access
- Relation
- ISSN: 10436618; PubMed ID: 34089868; CODEN: PHMRE
- Format
- Online
- Language
- English
- Type
- Review
Collection
Citation
Kuchi Bhotla H.; Meyyazhagan A.; Pappusamy M.; Park S.; Arumugam V.A.; Pushparaj K.; Rengasamy K.R.; Liu W.; Balasubramanian B., “Dietary nutrients and their control of the redox bioenergetic networks as therapeutics in redox dysfunctions sustained pathologies,” CHRIST (Deemed To Be University) Institutional Repository, accessed February 23, 2025, https://archives.christuniversity.in/items/show/21594.