Recent Trends in the Synthesis and Mechanistic Implications of Phenanthridines
- Title
- Recent Trends in the Synthesis and Mechanistic Implications of Phenanthridines
- Creator
- Talukdar V.; Vijayan A.; Kumar Katari N.; Radhakrishnan K.V.; Das P.
- Description
- Phenanthridine derivatives are one of the most intensively studied families of biologically active compounds. There has been considerable scientific interest in the turn of this century in the synthesis of these N-containing heterocycles as they are prevalent in many alkaloids and also possess striking biological activities including antibacterial, antifungal, antitumor activities. In this regard, a number of synthetic approaches toward the construction of phenanthridine moieties with various substituents, and to increase their yield have been developed by the synthetic organic community. Even though many researchers have developed various innovative methods for the synthesis of phenanthridine derivatives for the past few years, still there is substantial scope for the discovery of novel synthetic methods. In this review, the latest developments in the diverse synthetic strategies of phenanthridine derivatives in the presence and absence of metals were described. The present review also enlightens the use of different reagents, the diversity of the substrates identified, and the plausible mechanisms unravelled towards the construction of these biologically relevant scaffolds. (Figure presented.). 2021 Wiley-VCH GmbH
- Source
- Advanced Synthesis and Catalysis, Vol-363, No. 5, pp. 1202-1245.
- Date
- 2021-01-01
- Publisher
- Wiley-VCH Verlag
- Subject
- heteroaromatic; metal-free; metal-mediated; nitrogen-containing heterocycle; phenanthridine
- Coverage
- Talukdar V., Department of Chemistry, Indian Institute of Technology (Indian School of Mines), Dhanbad, 826004, India; Vijayan A., Department of Chemistry, CHRIST (Deemed to be University), Hosur road, Bengaluru, 560029, India; Kumar Katari N., Department of Chemistry, GITAM University, Hyderabad, 502329, India; Radhakrishnan K.V., CSIR National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram, 695019, India; Das P., Department of Chemistry, Indian Institute of Technology (Indian School of Mines), Dhanbad, 826004, India
- Rights
- Restricted Access
- Relation
- ISSN: 16154150; CODEN: ASCAF
- Format
- Online
- Language
- English
- Type
- Review
Collection
Citation
Talukdar V.; Vijayan A.; Kumar Katari N.; Radhakrishnan K.V.; Das P., “Recent Trends in the Synthesis and Mechanistic Implications of Phenanthridines,” CHRIST (Deemed To Be University) Institutional Repository, accessed February 23, 2025, https://archives.christuniversity.in/items/show/21604.