Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Short Survey Short survey Faculty Publications- Short Surveys Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Biotechnological approaches for the production of gymnemic acid from Gymnema sylvestre R. Br. Subject The topic of the resource Cell suspension culture; Elicitation; Gymnema sylvestre; Gymnemic acid; Organ culture Description An account of the resource Abstract : Diabetes is a chronic disease that affects several organs and can be treated using phytochemicals found in medicinal plants. Gymnema sylvestre (Asclepiadaceae) is one such medicinal plant rich in anti-diabetic properties. The plant is commonly known as madhunashini in Sanskrit because of its ability to cure diabetes (sugar). Gymnemic acid(GA) is a phytochemical (a triterpenoid saponin) responsible for the herbs main pharmacological activity. This secondary metabolite has a lot of potential as a phytochemical with pharmacological properties including nephroprotection, hypoglycemia, antioxidant, antimicrobial, and anti-inflammatory. Gymnema has acquired a lot of popularity in recent years due to its low side effects and high efficacy in healing diabetes, which has led to overexploitation by pharmaceutical enterprises for its biomass in the wild for the purification of gymnemic acid. Modern biotechnological techniques involving the establishment of cell and organ cultures from G. sylvestre will assist us in fulfilling the need for gymnemic acid production. The present review provides insights on the establishment of cell and organ cultures for the production of a potent antidiabetic molecule gymnemic acid. Further, the review also delves into the intricacies of the different strategies for improved production of gymnemic acid using various elicitors. There is huge potential for sustainable production of gymnemic acid which could be met by establishment of bioreactor scale production. Understanding and engineering the biosynthetic pathway could also lead to improved GA production. Key points: Gymnemic acid is one of the potential anti-diabetic molecules from madhunashini Cell and organ culture offers potential approach for gymnemic acid production Elicitation strategies have improved the gymnemic acid production Graphical Abstract: [Figure not available: see fulltext.] 2023, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature. Creator An entity primarily responsible for making the resource Al-Khayri J.M.; Sudheer W.N.; Banadka A.; Lakshmaiah V.V.; Nagella P.; Al-Mssallem M.Q.; Alessa F.M.; Rezk A.A. Source A related resource from which the described resource is derived Applied Microbiology and Biotechnology, Vol-107, No. 14, pp. 4459-4469. Publisher An entity responsible for making the resource available Springer Science and Business Media Deutschland GmbH Date A point or period of time associated with an event in the lifecycle of the resource 2023-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1007/s00253-023-12587-0" target="_blank" rel="noreferrer noopener">https://doi.org/10.1007/s00253-023-12587-0</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85160867906&amp;doi=10.1007%2Fs00253-023-12587-0&amp;partnerID=40&amp;md5=6b1b7ef8922af33f2886e9e2f4bcc76f" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85160867906&amp;doi=10.1007%2fs00253-023-12587-0&amp;partnerID=40&amp;md5=6b1b7ef8922af33f2886e9e2f4bcc76f</a> Rights Information about rights held in and over the resource Restricted Access Relation A related resource ISSN: 1757598; PubMed ID: 37266583; CODEN: AMBID Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Short survey Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Al-Khayri J.M., Department of Plant Biotechnology, College of Agriculture and Food Sciences, King Faisal University, Al-Ahsa 31982, Al Hofuf, Saudi Arabia; Sudheer W.N., Department of Life Sciences, CHRIST (Deemed to be University), Bangalore, 560029, India; Banadka A., Department of Life Sciences, CHRIST (Deemed to be University), Bangalore, 560029, India; Lakshmaiah V.V., Department of Life Sciences, CHRIST (Deemed to be University), Bangalore, 560029, India; Nagella P., Department of Life Sciences, CHRIST (Deemed to be University), Bangalore, 560029, India; Al-Mssallem M.Q., Department of Food Science and Nutrition, College of Agriculture and Food Sciences, King Faisal University, Al-Ahsa 31982, Al Hofuf, Saudi Arabia; Alessa F.M., Department of Food Science and Nutrition, College of Agriculture and Food Sciences, King Faisal University, Al-Ahsa 31982, Al Hofuf, Saudi Arabia; Rezk A.A., Department of Plant Biotechnology, College of Agriculture and Food Sciences, King Faisal University, Al-Ahsa 31982, Al Hofuf, Saudi Arabia