Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Faculty Publications Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Creator An entity primarily responsible for making the resource Nanda, Binita; Lakshmi, Chaitanya; Pandey, Chandra Mouli; Kumar, Ashwini; Thangavelu, Indumathi; Tadepalli, Srinivas; Bhran, Ahmed A. Title A name given to the resource Biocompatible Sodium Alginate Modified BaO2H2O2 Nanoparticles With Improved Therapeutic Efficacy Against Multidrug-Resistant Pathogens and Cancer Cells Date A point or period of time associated with an event in the lifecycle of the resource 01-01-2025 Source A related resource from which the described resource is derived Polymers for Advanced Technologies;Volume;36;Issue;10;Article No.;e70363; Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1002/pat.70363" target="_blank" rel="noreferrer noopener">https://doi.org/10.1002/pat.70363</a> <br /><br /><a href="https://www.scopus.com/pages/publications/105017842303?origin=resultslist" target="_blank" rel="noreferrer noopener">https://www.scopus.com/pages/publications/105017842303?origin=resultslist</a> Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Nanda B., Department of Chemistry, Siksha O Anusandhan (Deemed to be University), Bhubaneswar, India; Lakshmi C., Department of Chemistry, Presidency University, Bengaluru, India; Pandey C.M., Department of Chemistry, Faculty of Applied and Basic Sciences, SGT University, Gurgaon, India; Kumar A., Department of Mechanical, ARKA JAIN University, Jamshedpur, India; Thangavelu I., Department of Chemistry, CHRIST (Deemed to be University), Bangalore, India; Tadepalli S., Department of Chemical Engineering, College of Engineering, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia; Bhran A.A., Department of Chemical Engineering, College of Engineering, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia Description An account of the resource The increasing problem of multidrug-resistant pathogens and the limitations of conventional therapies for cancer treatments require designing new therapeutic agents. BaO2H2O2 and BaSA nanoparticles were prepared and characterized to determine their antimicrobial, antifungal, and anticancer activities. The XRD confirmed the crystallite sizes to be 34 nm for BaO2H2O2 and 25 nm for BaSA. The UVvisible analysis confirmed the band gap energies as 4.13 and 4.11 eV for BaO2H2O2 and BaSA, respectively. A shift in the blue-green PL emission from 488510 nm in BaO2H2O2 to 535 nm in BaSA indicated increased oxygen vacancies. EDAX analysis demonstrated elemental variations due to SA modification, whereas DLS measurements showed a decrease in the mean size of the nanoparticles from 116.70 nm (BaO2H2O2) to 111.90 nm (BaSA). Antimicrobial activity was shown against Klebsiella pneumoniae, Shigella dysenteriae, Escherichia coli, Pseudomonas aeruginosa, and Proteus vulgaris, while a considerable enhancement of antifungal activity against Candida albicans was observed in BaSA. Against MG-63 osteosarcoma cells, BaSA exhibited lower IC50 values (21.5, 20.2, 18.7 ?g mL?1 at 24, 48, and 72 h) when compared with BaO2H2O2 (23.4, 22.5, 21.3 ?g mL?1). Zebrafish embryos tolerated BaSA at 0.5 mg mL?1, with developmental abnormalities observed only at 1.0 mg mL?1. 2025 John Wiley &amp; Sons Ltd. Subject The topic of the resource antibacterial; anticancer; antifungal; barium peroxide; SA; surface modification Publisher An entity responsible for making the resource available John Wiley and Sons Ltd Relation A related resource ISSN: 10427147; Language A language of the resource English Type The nature or genre of the resource Article Rights Information about rights held in and over the resource Restricted Access; Hardcopy may be available in the library Format The file format, physical medium, or dimensions of the resource online