Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Faculty Publications Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Creator An entity primarily responsible for making the resource Tadepalli, Srinivas; Rathore, Mahendra Singh; Ballal, Suhas; Thangavelu, Indumathi; Gadallah, Abdelrahman G. Title A name given to the resource Biogenic Carboxymethyl Cellulose and L-Histidine Coated Barium Peroxide Nanocomposite: A Tri-Functional Platform Targeting Antimicrobial Resistance, Cancer, and Oxidative Stress Date A point or period of time associated with an event in the lifecycle of the resource 01-01-2026 Source A related resource from which the described resource is derived Polymers for Advanced Technologies;Volume;37;Issue;1;Article No.;e70508; Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1002/pat.70508" target="_blank" rel="noreferrer noopener">https://doi.org/10.1002/pat.70508</a> <br /><br /><a href="https://www.scopus.com/pages/publications/105028264937?origin=resultslist" target="_blank" rel="noreferrer noopener">https://www.scopus.com/pages/publications/105028264937?origin=resultslist</a> Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Tadepalli S., Department of Chemical Engineering, College of Engineering, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia; Rathore M.S., Department of Applied Science, PIT, Parul University, Gujarat, Vadodara, India; Ballal S., Department of Biochemistry, School of Sciences, JAIN (Deemed-to-be University), Karnataka, India; Thangavelu I., Department of Chemistry, CHRIST (Deemed to be University), Bangalore, India; Gadallah A.G., Department of Chemical Engineering, College of Engineering, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia Description An account of the resource The study addresses the urgent need for novel therapeutic agents in combating multidrug-resistant pathogens, cancer, and oxidative stress-related diseases. Barium peroxide (BaO2) nanoparticles and its novel nanocomposite, carboxymethyl cellulose and L-histidine coated BaO2 (BaO2-CMC-LH) were synthesized, characterized, and evaluated for their antibacterial, anticancer, and DPPH radical scavenging activities. Structural and functional characterizations were carried out using various analytical techniques. Biological evaluations demonstrated enhanced antibacterial activity against Methicillin-resistant Staphylococcus aureus (MRSA) and Candida albicans (C. albicans), with BaO2-CMC-LH exhibiting superior inhibition zones compared to BaO2. For MRSA, the zone of inhibition (ZOI) for BaO2 is about 9 mm, whereas the BaO2-CMC-LH nanocomposite exhibits a substantially larger ZOI of 21 mm. Likewise, for C. albicans, BaO2 presents a ZOI of 12 mm, and BaO2-CMC-LH exhibits a greater inhibition zone of 18 mm. Cytotoxicity analysis against osteosarcoma MG-63 cells revealed significantly improved anticancer activity, with BaO2-CMC-LH achieving an IC?? value of 28.6 ?g/mL compared to 53.3 ?g/mL for BaO2. The 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging assay showed that the BaO2-CMC-LH nanocomposite (78.45%) had activity compared to BaO2 alone (64.43%). These findings underscore the synergistic effects of the CMC-LH matrix in enhancing BaO2's biological activities, positioning BaO2-CMC-LH as a promising multifunctional therapeutic agent for addressing global health challenges. 2026 John Wiley &amp; Sons Ltd. Subject The topic of the resource barium peroxide; Candida albicans; carboxymethyl cellulose; DPPH free radical scavenging assay; L-histidine; MRSA; osteosarcoma MG-63 Publisher An entity responsible for making the resource available John Wiley and Sons Ltd Relation A related resource ISSN: 10427147; Language A language of the resource English Type The nature or genre of the resource Article Rights Information about rights held in and over the resource All Open Access; Bronze Open Access Format The file format, physical medium, or dimensions of the resource online