Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Faculty Publications Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Creator An entity primarily responsible for making the resource Gadallah, Abdelrahman G.; Thangavelu, Indumathi; Tadepalli, Srinivas; Arulselvan, Palanisamy Title A name given to the resource Pluronic F127Folic Acid Modified Nickel Oxide Nanocomposites via a Facile One-Pot Approach for InVitro Anticancer, Antibacterial, and DPPH Radical Scavenging Studies Date A point or period of time associated with an event in the lifecycle of the resource 01-01-2026 Source A related resource from which the described resource is derived Polymers for Advanced Technologies;Volume;37;Issue;2;Article No.;e70531; Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1002/pat.70531" target="_blank" rel="noreferrer noopener">https://doi.org/10.1002/pat.70531</a> <br /><br /><a href="https://www.scopus.com/pages/publications/105029529706?origin=resultslist" target="_blank" rel="noreferrer noopener">https://www.scopus.com/pages/publications/105029529706?origin=resultslist</a> Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Gadallah A.G., Department of Chemical Engineering, College of Engineering, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia; Thangavelu I., Department of Chemistry, CHRIST (Deemed To Be University), Bangalore, India; Tadepalli S., Department of Chemical Engineering, College of Engineering, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia; Arulselvan P., Department of Biochemistry, Karpagam Academy of Higher Education (Deemed to be University), Tamil Nadu, Coimbatore, India Description An account of the resource Drug-resistant bacteria and cancer remain major challenges in healthcare, highlighting the need for multifunctional nanomaterials. In this study, folic acid- and Pluronic F127-modified nickel oxide nanocomposites (NiOPF127FA) were synthesized via a one-pot method, and their invitro antibacterial, antioxidant, and anticancer properties were evaluated. XRD analysis showed a crystallite size of 19.42 nm for NiOPF127FA, while PL spectra exhibited a green emission peak at 507 nm, indicative of structural defects in the NiO lattice. NiOPF127FA displayed enhanced antibacterial activity against MRSA and Candida albicans compared to bare NiO, as evidenced by larger inhibition zones and lower MIC and MBC values. The DPPH assay demonstrated improved radical scavenging activity of the modified nanocomposites, likely related to their smaller size, higher surface area, and surface defect-mediated electron transfer. Invitro anticancer studies using rat C6 glioblastoma cells revealed dose-dependent decreases in cell viability, with IC50 values of 12.3 ?g/mL for NiO and 9.6 ?g/mL for NiOPF127FA. Fluorescence staining with AO/EB and DAPI indicated morphological changes in nuclei and alterations in MMP, consistent with induction of cell death. Overall, these findings suggest that NiOPF127FA nanocomposites exhibit improved invitro biological activity, providing a foundation for further preclinical investigations of their potential biomedical applications. 2026 John Wiley &amp; Sons Ltd. Subject The topic of the resource antimicrobial activity; apoptosis; glioma cancer; mitochondrial membrane potential; NiO; NiO-PF 127-FA Publisher An entity responsible for making the resource available John Wiley and Sons Ltd Relation A related resource ISSN: 10427147; Language A language of the resource English Type The nature or genre of the resource Article Rights Information about rights held in and over the resource Restricted Access; Hardcopy may be available in the library Format The file format, physical medium, or dimensions of the resource online