Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Faculty Publications Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Creator An entity primarily responsible for making the resource Choudhary, Binod Kr; Achary, Patnala Ganga Raju; Devakki, Basavaraj; Kapoor, Shalini; Thangavelu, Indumathi; Tadepalli, Srinivas; Bhran, Ahmed A Title A name given to the resource Synthesis and characterization of SnO2-SA-FA nanocomposite for anticancer (cervical cancer HeLa cells), antimicrobial (methicillin-resistant Staphylococcus aureus, Candida albicans) and antioxidant activities Date A point or period of time associated with an event in the lifecycle of the resource 01-01-2026 Source A related resource from which the described resource is derived Polymer International; Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1002/pi.70148" target="_blank" rel="noreferrer noopener">https://doi.org/10.1002/pi.70148</a> <br /><br /><a href="https://www.scopus.com/pages/publications/105040390863?origin=resultslist" target="_blank" rel="noreferrer noopener">https://www.scopus.com/pages/publications/105040390863?origin=resultslist</a> Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Choudhary B.K., Department of Mechanical, ARKA JAIN University, Jamshedpur, India; Achary P.G.R., Department of chemistry, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar, India; Devakki B., Department of Mechanical Engineering, Presidency University, Bengaluru, India; Kapoor S., Department of Periodontology, Faculty of Dental Sciences, SGT University, Gurugram, India; Thangavelu I., Department of Chemistry, CHRIST (Deemed to be University), Bangalore, India; Tadepalli S., Department of Chemical Engineering, College of Engineering, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia; Bhran A.A., Department of Chemical Engineering, College of Engineering, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia Description An account of the resource This study reports the synthesis and characterization of a novel sodium alginate (SA) and folic acid (FA) functionalized tin oxide nanocomposite (SnO2-SA-FA) and investigates its antimicrobial, antioxidant and anticancer properties. XRD analysis confirmed the tetragonal crystalline structure of SnO2, while the crystallite size decreased from 28.3 nm for pure SnO2 to 22.1 nm after functionalization, indicating enhanced surface area and reactivity. UVvisible analysis revealed a reduction in bandgap energy from 3.6 to 3.4 eV, suggesting improved charge transfer capability. Photoluminescence studies showed green emission at 506 nm, indicating enhanced oxygen vacancy defects and reactive oxygen species (ROS) generation. The SnO2-SA-FA nanocomposite demonstrated enhanced antimicrobial activity against methicillin-resistant Staphylococcus aureus and Candida albicans, exhibiting zones of inhibition of 20 mm and 17 mm, respectively, with minimum bactericidal concentration values of 1600 ?g mL?1. Antioxidant studies revealed significantly improved 2,2-diphenyl-1-picrylhydrazyl radical scavenging activity, reaching 83.23% at 100 ?g mL?1 compared to 66.34% for pure SnO? nanoparticles. Cytotoxicity studies against HeLa cervical cancer cells demonstrated dose-dependent anticancer activity, with the SnO2-SA-FA nanocomposite exhibiting a lower IC50 value (concentration required to inhibit 50% of cell viability) (40.6 ?g mL?1) than pure SnO? nanoparticles (58.2 ?g mL?1). Fluorescence microscopy confirmed enhanced apoptosis induction through ROS-mediated oxidative stress and folate-receptor-targeted uptake. Furthermore, biocompatibility studies on L929 fibroblast cells showed cell viability above 80%, confirming low toxicity and favorable biological safety. These findings demonstrate that the SnO2-SA-FA nanocomposite is a promising multifunctional nanoplatform for antimicrobial, antioxidant and targeted anticancer biomedical applications. 2026 Society of Chemical Industry. 2026 Society of Chemical Industry. Subject The topic of the resource antimicrobial activity; antioxidant activity; cervical cancer; folic acid; SnO₂ nanoparticles; sodium alginate Publisher An entity responsible for making the resource available John Wiley and Sons Ltd Relation A related resource ISSN: 9598103; Language A language of the resource English Type The nature or genre of the resource Article Rights Information about rights held in and over the resource Restricted Access; Hardcopy may be available in the library Format The file format, physical medium, or dimensions of the resource online