Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Faculty Publications Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Creator An entity primarily responsible for making the resource Thakore, Sanketsinh; Saini, Rajat; Kushwaha, Ravi kant; Asha, K.; Thangavelu, Indumathi; AlGhamdi, AbdulAziz A.; Tadepalli, Srinivas Title A name given to the resource Design and characterization of SrO2-CMC-Dcar nanocomposite with enhanced antimicrobial, anticancer, and antioxidant activities Date A point or period of time associated with an event in the lifecycle of the resource 01-01-2026 Source A related resource from which the described resource is derived Naunyn-Schmiedeberg's Archives of Pharmacology;Volume;399;Issue;1;pp.441-458 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1007/s00210-025-04415-1" target="_blank" rel="noreferrer noopener">https://doi.org/10.1007/s00210-025-04415-1</a> <br /><br /><a href="https://www.scopus.com/pages/publications/105010083594?origin=resultslist" target="_blank" rel="noreferrer noopener">https://www.scopus.com/pages/publications/105010083594?origin=resultslist</a> Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Thakore S., Department of Applied Science, PIT, Parul University, Gujarat, Vadodara, India; Saini R., Centre of Research Impact and Outcome, Chitkara University, Punjab, Rajpura, 140417, India; Kushwaha R.K., Maharishi School of Pharmaceutical Sciences, Maharishi University of Information Technology, Uttar Pradesh, Lucknow, India; Asha K., Department of Life Sciences, School of Sciences, JAIN (Deemed-to-be University), Karnataka, Bengaluru, India; Thangavelu I., Department of Chemistry, CHRIST (Deemed to be University), Bangalore, 560029, India; AlGhamdi A.A., Department of Chemical Engineering, College of Engineering, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, 11432, Saudi Arabia; Tadepalli S., Department of Chemical Engineering, College of Engineering, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, 11432, Saudi Arabia Description An account of the resource HeLa cervical cancer cells exhibit high aggressiveness and proliferation, highlighting the need for novel therapies. Nanocomposite synthesis offers a promising approach due to its enhanced bioavailability, targeted delivery, and selective cytotoxicity. Thus, carboxymethyl cellulose (CMC) and D-carvone (Dcar)-coated strontium oxide (SrO2) (SrO2-CMC-Dcar) nanocomposite were synthesized using a wet chemical method. Structural and morphological characterization using XRD, FTIR, PL spectroscopy, DLS, HRTEM, and XPS confirmed the successful synthesis of the nanocomposite. XRD analysis revealed that the crystallite sizes of SrO2 and SrO2-CMC-Dcar were 38nm and 29nm, respectively. PL spectra revealed prominent green emission at 516, 524, and 535nm, indicating that oxygen vacancies are associated with ROS generation. DLS analysis revealed that pure SrO2 exhibited a particle size distribution of 128.7nm, while the SrO2-CMC-Dcar nanocomposite showed an increased size of 244.80nm. The nanocomposite demonstrated an enhanced antimicrobial activity against MRSA and Candida albicans when compared to SrO2 alone. Furthermore, MTT assay results revealed that the SrO2CMCDcar composite significantly decreased HeLa cell viability to 11.94%, and the IC50 value was found to be 50.2 and 39.7 for SrO2 and nanocomposite SrO2-CMC-Dcar, respectively, confirming it enhanced anticancer potential. In addition, the SrO2-CMC-Dcar nanocomposite exhibited enhanced antioxidant properties demonstrated by DPPH free radical scavenging assays. These findings suggest that the SrO2-CMC-Dcar nanocomposite holds promise for therapeutic applications in combating cancer, microbial infections, and oxidative stress. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2025. Subject The topic of the resource Antibacterial; Anticancer; Antioxidant; Nanocomposite; SrO?-CMC-Dcar Publisher An entity responsible for making the resource available Springer Science and Business Media Deutschland GmbH Relation A related resource ISSN: 281298; CODEN: NSAPC Language A language of the resource English Type The nature or genre of the resource Article Rights Information about rights held in and over the resource Restricted Access; Hardcopy may be available in the library Format The file format, physical medium, or dimensions of the resource online