Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Faculty Publications Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Creator An entity primarily responsible for making the resource R, Shashikala A.; Chaudhary, Sarita; Adil, Shaikh; Rout, Sudhanshu; Thangavelu, Indumathi; Tadepalli, Srinivas; Gadallah, Abdelrahman G. Title A name given to the resource Pluronic F127-functionalized cerium fluoride nanocomposite: synthesis, characterization, and its enhanced antibacterial activities Date A point or period of time associated with an event in the lifecycle of the resource 01-01-2026 Source A related resource from which the described resource is derived Naunyn-Schmiedeberg's Archives of Pharmacology; Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1007/s00210-026-05398-3" target="_blank" rel="noreferrer noopener">https://doi.org/10.1007/s00210-026-05398-3</a> <br /><br /><a href="https://www.scopus.com/pages/publications/105037867459?origin=resultslist" target="_blank" rel="noreferrer noopener">https://www.scopus.com/pages/publications/105037867459?origin=resultslist</a> Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant R S.A., Department of Chemistry, Presidency University, Karnataka, Bengaluru, 560064, India; Chaudhary S., Department of FBAS (Chemistry), Vivekananda Global University, Jaipur, 303012, India; Adil S., Department of Dairy Technology, Faculty of Engineering and Technology, Parul Institute of Technology, Parul University, Gujarat, Vadodara, 391760, India; Rout S., Department of Pharmaceutical Sciences, School of Pharmaceutical Sciences, Siksha O Anusandhan (Deemed to Be University), Odisha, Bhubaneswar, 751030, India; Thangavelu I., Department of Chemistry, CHRIST (Deemed to Be University), Bangalore, 560029, India; Tadepalli S., Department of Chemical Engineering, College of Engineering, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, 11432, Saudi Arabia; Gadallah A.G., Department of Chemical Engineering, College of Engineering, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, 11432, Saudi Arabia Description An account of the resource The persistence of pathogenic bacteria, rising antibiotic resistance, and the ongoing need for effective anticancer agents necessitate the development of advanced multifunctional therapeutic strategies. In this study, CeF? nanoparticles and PF127-functionalized CeF? (CeF?PF127) nanocomposites were synthesized via a facile wet chemical route and systematically characterized for their structural, optical, and biological properties. XRD confirmed the formation of phase-pure hexagonal CeF? with crystallite sizes of 31nm (CeF?) and 27nm (CeF?PF127), while SAED revealed lattice fringes of approximately 0.27nm (CeF?) and 0.29nm (CeF?PF127). EDAX and XPS validated the Ce/F stoichiometry and the successful surface functionalization with PF127. Optical analyses showed a slight reduction in band gap from 3.15 to 3.09eV upon polymer coating, and PL spectra indicated enhanced defect-related emission in CeF?PF127, suggesting stabilization of Ce3? ions and oxygen vacancy sites. Biological evaluations demonstrated that CeF?PF127 exhibited superior antioxidant activity (DPPH assay) and enhanced anticancer efficacy against MG-63 osteosarcoma cells, with lower IC?? values over 2472h. Antibacterial studies against S. aureus, B. subtilis, K. pneumoniae, and S. dysenteriae revealed larger inhibition zones (1820.5mm) and improved MIC/MBC values (600/1000gmL?1) compared to bare CeF?. Biocompatibility assessment using L929 fibroblasts confirmed cell viability exceeding 80% for both samples. Collectively, these results demonstrate that CeF?PF127 is a stable, multifunctional nanocomposite with promising potential for biomedical applications. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2026. Subject The topic of the resource Antibacterial and anticancer activity; Antioxidant properties; Biocompatible nanomaterials; CeF? nanoparticles; CeF?PF127 nanocomposite Publisher An entity responsible for making the resource available Springer Science and Business Media Deutschland GmbH Relation A related resource ISSN: 281298; CODEN: NSAPC Language A language of the resource English Type The nature or genre of the resource Article Rights Information about rights held in and over the resource Restricted Access; Hardcopy may be available in the library Format The file format, physical medium, or dimensions of the resource online