Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Faculty Publications Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Creator An entity primarily responsible for making the resource Bhalla, Vijay; Sahu, Chandra Prabha; Shashikala, A.R.; Singh, Sulochana; Thangavelu, Indumathi; Tadepalli, Srinivas; Bhran, Ahmed A. Title A name given to the resource Synthesis and Multifunctional Evaluation of BaO?-Sodium Alginate-Curcumin Nanocomposite: Improved Antibacterial, Antioxidant, and Osteosarcoma Cell Inhibition Date A point or period of time associated with an event in the lifecycle of the resource 01-01-2026 Source A related resource from which the described resource is derived Journal of Inorganic and Organometallic Polymers and Materials;Volume;36;Issue;1;pp.259-278 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1007/s10904-025-03916-z" target="_blank" rel="noreferrer noopener">https://doi.org/10.1007/s10904-025-03916-z</a> <br /><br /><a href="https://www.scopus.com/pages/publications/105010606137?origin=resultslist" target="_blank" rel="noreferrer noopener">https://www.scopus.com/pages/publications/105010606137?origin=resultslist</a> Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Bhalla V., Department of Pharmaceutics, College of Pharmacy, SGT University, Haryana, Gurugram, India; Sahu C.P., Department of Electrical &amp; Electronics, ARKA JAIN University, Jharkhand, Jamshedpur, India; Shashikala A.R., Department of Chemistry, Presidency University, Karnataka, Bengaluru, India; Singh S., Department of Chemistry, Siksha O Anusandhan (Deemed to be University), Odisha, Bhubaneswar, 751030, India; Thangavelu I., Department of Chemistry, CHRIST (Deemed to be University), Karnataka, Bangalore, 560029, India; Tadepalli S., Department of Chemical Engineering, College of Engineering, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, 11432, Saudi Arabia; Bhran A.A., Department of Chemical Engineering, College of Engineering, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, 11432, Saudi Arabia Description An account of the resource Nanotechnology-based strategies provide a promising platform for developing multifunctional materials with enhanced antibacterial, antioxidant, and anticancer properties, offering effective solutions for combating infections, oxidative stress, and osteosarcoma cell proliferation. In the current study BaO2-sodium alginate-curcumin (BaO?-SA-Cur) was prepared by facile wet chemical route. The structural and morphological characteristics of the composite were ascertained using extensive characterization techniques. The crystallite size was found to be 52.2nm for BaO2 and 43.1nm for BaO2-SA-Cur nanocomposite as per XRD analysis. UV-visible spectroscopy results revealed that the band gap was found as 4.54eV for BaO2-SA-Cur nanocomposite and 4.38eV for BaO2 nanoparticles. PL studies revealed that the BaO2-SA-Cur nanocomposite exhibited intense emission peaks at 379nm, 421nm, 448nm, 477nm, and 508nm. DLS analysis revealed that the pure BaO2 exhibited the particle size around 118.70 5.4nm while the BaO?-SA-Cur nanocomposite around 139.50 7.8nm and more dispersion in the solution. The BaO?-SA-Cur nanocomposite exhibited enhanced antibacterial action against multi-resistant gram-negative bacterial species (Klebsiella pneumoniae, Escherichia coli, Shigella dysenteriae, Proteus vulgaris, and Pseudomonas aeruginosa) than that of pure BaO? and comparable with streptomycin. Importantly, the nanocomposite revealed remarkable anticancer activity against the osteosarcoma MG-63 cells where Cur was synergistically inducing cell apoptosis. The IC50 value was calculated as 45.7 for undoped BaO2 and 35.6 for doped BaO2-SA-Cur composite. Biocompatibility studies on L929 fibroblast cells showed over 85% cell viability for BaO?-SA-Cur, confirming its low cytotoxicity and suitability for biomedical applications. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2025. Subject The topic of the resource Antibacterial; Anticancer (MG-63 osteosarcoma cells); Antioxidant activities; BaO?-SA-Cur nanocomposite; PL emission Publisher An entity responsible for making the resource available Springer Relation A related resource ISSN: 15741443; Language A language of the resource English Type The nature or genre of the resource Article Rights Information about rights held in and over the resource Restricted Access; Hardcopy may be available in the library Format The file format, physical medium, or dimensions of the resource online