Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Faculty Publications Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Creator An entity primarily responsible for making the resource PadmaPriya, G.; Joshi, Anand; Sachdeva, Ankit; Arun, Jagdish Kumar; AlGhamdi, AbdulAziz A.; Tadepalli, Srinivas; Thangavelu, Indumathi Title A name given to the resource Multifunctional SrO?Sodium AlginateL-Arginine Nanocomposite: A Green Approach against Colon Cancer and Pathogenic Microbes Date A point or period of time associated with an event in the lifecycle of the resource 01-01-2025 Source A related resource from which the described resource is derived Journal of Polymers and the Environment;Volume;33;Issue;10;pp.4378-4394 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1007/s10924-025-03655-9" target="_blank" rel="noreferrer noopener">https://doi.org/10.1007/s10924-025-03655-9</a> <br /><br /><a href="https://www.scopus.com/pages/publications/105012563459?origin=resultslist" target="_blank" rel="noreferrer noopener">https://www.scopus.com/pages/publications/105012563459?origin=resultslist</a> Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant PadmaPriya G., Department of Chemistry and Biochemistry, JAIN (Deemed-to-be University), Karnataka, Bangalore, 560069, India; Joshi A., Department of Mechatronics Engineering, PIT, Parul University, Gujarat, Vadodara, 391760, India; Sachdeva A., Center of Research Impact and Outcome, Chitkara University, Punjab, Rajpura, 140417, India; Arun J.K., Department of Sciences, Vivekananda Global University, Jaipur, 303012, India; AlGhamdi A.A., Department of Chemical Engineering, College of Engineering, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, 11432, Saudi Arabia; Tadepalli S., Department of Chemical Engineering, College of Engineering, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, 11432, Saudi Arabia; Thangavelu I., Department of Chemistry, CHRIST (Deemed to be University), Karnataka, Bangalore, 560029, India Description An account of the resource Pathogenic microbes pose a significant threat to human health due to their increasing resistance to standard antibiotics. Colon cancer is among the deadliest forms of cancer worldwide and often exhibits resistance to conventional treatments, highlighting the urgent need for alternative therapeutic agents. In this study, a SrO2SALA nanocomposite was synthesized via a green chemical approach using Bougainvillea glabra extract and evaluated for its anticancer, antioxidant, and antimicrobial potential. In this work, SrO2-SA-LA nanocomposite was prepared via a green chemical approach using Bougainvillea glabra extract and evaluated for its potential anticancer, antioxidant, and antimicrobial properties. The nanocomposite was successfully synthesized and functionalized, as confirmed by characterization studies. XRD revealed a crystalline phase of tetragonal SrO2. The calculated optical bandgap energies were 4.11eV for pristine SrO2 and 4.35eV for SrO2-SA-LA nanocomposite. DLS analysis indicated median particle sizes of 128.40nm and 142.70nm for SrO? and SrO2SALA, respectively. PL studies showed that the SrO2SALA nanocomposite exhibited green emission in the range of 494534nm, suggesting an increase in oxygen-related defect states compared to pure SrO2. Disc diffusion assay revealed that SrO2-SA-LA nanocomposite exhibited enhanced antimicrobial activity against common disease-causing pathogens, while MTT assay showed enhanced cytotoxicity against HCT-116 colon cancer cells. Additionally, the SrO2-SA-LA nanocomposite exhibited superior free radical scavenging in DPPH assays, indicating high antioxidant potential. Furthermore, cytocompatibility studies using L929 fibroblast cells confirmed that both SrO? and SrO?SALA nanocomposite are non-toxic to normal cells, with cell viability exceeding 80%, indicating their biosafety. The results suggest that SrO2-SA-LA nanocomposite is a promising candidate for applications in anticancer, antioxidant, and antimicrobial therapies with good biocompatibility. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2025. Subject The topic of the resource Biomedical application; Bougainvillea Glabra extract; Green synthesis; L-arginine; Sodium alginate; SrO₂ Publisher An entity responsible for making the resource available Springer Relation A related resource ISSN: 15662543; CODEN: JPENF Language A language of the resource English Type The nature or genre of the resource Article Rights Information about rights held in and over the resource Restricted Access; Hardcopy may be available in the library Format The file format, physical medium, or dimensions of the resource online