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            <name>Title</name>
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                <text>Faculty Publications</text>
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    <name>Article</name>
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          <name>Creator</name>
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              <text>Pasha, Mahaboob; Sharma, Deeplata; Khambhati, Dimpal Prafulchandra; Maharana, Laxmidhar; Thangavelu, Indumathi; Tadepalli, Srinivas; Bhran, Ahmed A.</text>
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          <name>Title</name>
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              <text>L-arginine functionalized NiFe?O? nanoparticles: synthesis, characterization, antimicrobial activity, and biocompatibility evaluation in a zebrafish model</text>
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          <name>Date</name>
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              <text>01-01-2026</text>
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          <name>Source</name>
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              <text>World Journal of Microbiology and Biotechnology;Volume;42;Issue;3;Article No.;133;</text>
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          <name>Identifier</name>
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              <text>&lt;a href="https://doi.org/10.1007/s11274-026-04853-w" target="_blank" rel="noreferrer noopener"&gt;https://doi.org/10.1007/s11274-026-04853-w&lt;/a&gt; &lt;br /&gt;&lt;br /&gt;&lt;a href="https://www.scopus.com/pages/publications/105033328328?origin=resultslist" target="_blank" rel="noreferrer noopener"&gt;https://www.scopus.com/pages/publications/105033328328?origin=resultslist&lt;/a&gt;</text>
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              <text>Pasha M., Department of Physics, Presidency University, Karnataka, Bengaluru, India; Sharma D., Department of FBAS (Chemistry), Vivekananda Global University, Jaipur, India; Khambhati D.P., Department of Biomedical Engineering, Faculty of Engineering and Technology, Parul Institute of Technology, Parul University, Gujarat, Vadodara, India; Maharana L., Department of Pharmaceutical Sciences, School of Pharmaceutical Sciences, Siksha O Anusandhan (Deemed to be University), Odisha, Bhubaneswar, India; Thangavelu I., Department of Chemistry, CHRIST (Deemed to be University), Karnataka, Bangalore, 560029, India; Tadepalli S., Department of Chemical Engineering, College of Engineering, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, 11432, Saudi Arabia; Bhran A.A., Department of Chemical Engineering, College of Engineering, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, 11432, Saudi Arabia</text>
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              <text>NiFe?O? nanoparticles and L-argininefunctionalized NiFe?O? (NiFe?O4LA) were synthesized, characterized, and evaluated for antimicrobial performance and in vivo biocompatibility in a zebrafish embryo model. The XRD and HRTEM studies confirmed the formation of single-phase cubic spinel NiFe?O? with average crystallite size ? 2030nm. Surface modification with LA preserved the spinel structure while reducing crystallinity and hydrodynamic size 128.7nm. FTIR and XPS verified successful surface functionalization. UV vis measurements showed band-gap narrowing after La conjugation (Eg ? 3.23 ? 3.15eV). NiFe?O?LA exhibited enhanced antimicrobial activity compared with bare NiFe?O? against MRSA and C. albicans an effect attributed to enhanced surface interaction and ROS-mediated oxidative damage. The MIC values of C. albicans is found to 1200g/mL while in the case MRSA is about 900g/mL. The ROS assays with histidine modulation supported a role for redox activity in antimicrobial action. In vivo zebrafish embryo assays showed minimal developmental toxicity at tested exposures with better viability for the LA coated material.  The Author(s), under exclusive licence to Springer Nature B.V. 2026.</text>
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              <text>Antimicrobial activity; Biocompatibility; LA functionalization; Nano biomaterials; NiFe?O? nanoparticles; ROS; Spinel ferrite; Zebrafish embryo model</text>
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              <text>Springer Science and Business Media B.V.</text>
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              <text>ISSN: 9593993; CODEN: WJMBE</text>
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              <text>English</text>
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              <text>Restricted Access; Hardcopy may be available in the library</text>
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              <text>online</text>
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