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              <text>Salim, Sneha; Vijayalakshmi, A.</text>
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              <text>Segmentation of overlapping leukemic cells in histopathological images using HSV- based watershed transformation</text>
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              <text>International Journal of Information Technology (Singapore);</text>
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              <text>&lt;a href="https://doi.org/10.1007/s41870-025-02998-9" target="_blank" rel="noreferrer noopener"&gt;https://doi.org/10.1007/s41870-025-02998-9&lt;/a&gt; &lt;br /&gt;&lt;br /&gt;&lt;a href="https://www.scopus.com/pages/publications/105024347242?origin=resultslist" target="_blank" rel="noreferrer noopener"&gt;https://www.scopus.com/pages/publications/105024347242?origin=resultslist&lt;/a&gt;</text>
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              <text>Salim S., Department of Statistics and Data Science, Christ University, Bengaluru, India; Vijayalakshmi A., Department of Statistics and Data Science, Christ University, Bengaluru, India</text>
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              <text>Accurate segmentation of white blood cells (WBCs) is essential for computer-aided diagnosis, as overlapping and densely clustered cells often present significant challenges. This work introduces a hybrid framework for segmentation that proposes a fusion of hue and saturation in the Hue Saturation Value (HSV) domain. Gaussian smoothing, Otsu thresholding, and Morphological refinement is employed to enhance cell contrast and eliminate noise. A marker-based watershed algorithm is subsequently applied for accurate separation of overlapping WBCs. Evaluation on the ALL-IDB2 dataset confirms the methods capability through achieving a Dice Similarity Coefficient(DSC) of 0.8929 and an Intersection over Union (IoU) of 0.8099 to produce well-defined cellular boundaries. The novelty of this study lies in the integrated hue-saturation fusion and marker-based watershed strategy, offering improved boundary localization and reliable segmentation of overlapping WBCs.  Bharati Vidyapeeth's Institute of Computer Applications and Management 2025.</text>
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              <text>HSV color space; Marker-Watershed segmentation; Overlapped cells; Segmentation; White blood cells (WBCs)</text>
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              <text>Springer Science and Business Media B.V.</text>
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              <text>ISSN: 25112104;</text>
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