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                <text>Faculty Publications</text>
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              <text>Servesh, Anushka; Ramaraj, Sankar Ganesh; Rajprasad, J.; Tabassum, Sumaiya; Govindaraju, Santhosh</text>
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              <text>Blue LED photolytic method for the synthesis of 1,4-dihydropyridine derivatives from benzo [b]thiophene-2-carbaldehyde</text>
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              <text>01-01-2025</text>
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              <text>Chemical Engineering and Processing - Process Intensification;Volume;209;Issue;;Article No.;110205;</text>
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              <text>&lt;a href="https://doi.org/10.1016/j.cep.2025.110205" target="_blank" rel="noreferrer noopener"&gt;https://doi.org/10.1016/j.cep.2025.110205&lt;/a&gt; &lt;br /&gt;&lt;br /&gt;&lt;a href="https://www.scopus.com/pages/publications/85217089511?origin=resultslist" target="_blank" rel="noreferrer noopener"&gt;https://www.scopus.com/pages/publications/85217089511?origin=resultslist&lt;/a&gt;</text>
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              <text>Servesh A., Department of Chemistry, Christ University, Hosur Road, Bengaluru, 560029, India; Ramaraj S.G., Department of Bioengineering, of Engineering, The University of Tokyo, Hongo, 7-3-1, Japan, Department of Materials Physics, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences (SIMTS), Thandalam, Tamilnadu, Chennai, 602105, India; Rajprasad J., Department of Civil Engineering, College of Engineering and Technology, SRM Institute of Science and Technology, Tamilnadu, Kattankulathur, 603203, India; Tabassum S., Department of Chemistry, Surana College - Autonomous, South End Road, Bengaluru, 560004, India; Govindaraju S., Department of Sciences and Humanities, Christ University, School of Engineering and Technology, Kumbalagodu, Mysore Road, Bengaluru, 560074, India</text>
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              <text>This study presents a highly efficient and operationally simple protocol for synthesizing 1,4-dihydropyridine derivatives. The protocol uses an inexpensive and readily available photocatalyst Mn2(CO)10, which plays a crucial role in the single-pot, four-component reaction involving benzo [b]thiophene-2-carbaldehyde, malononitrile, dialkyl acetylene dicarboxylate, and anilines in a blue LED (400500 nm) photocatalytic technique. The reaction conditions include the use of blue LEDs, a lower catalyst load, and green solvents like dimethyl sulfoxide (DMSO) and water in a 1:1 ratio. The multicomponent photocatalytic approach negates the use of expensive catalysts and the necessity of multi-step routes, in addition to providing better atom economy and an easy work-up process, and it is environmentally benign. The derivatives were effectively synthesized in higher yields and characterized using 1H NMR, 13C NMR, and ESI-MS. The obtained 1,4 dihydropyridines also have tremendous capability for biological and pharmacological activities, opening exciting possibilities for future research and applications.  2025</text>
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              <text>Atom economy; Blue led; Four-component synthesis; Green synthesis; Multicomponent reaction; Photocatalyst; Single-pot; Triethyl amine</text>
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              <text>Elsevier B.V.</text>
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              <text>ISSN: 2552701; CODEN: CENPE</text>
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              <text>All Open Access; Hybrid Gold Open Access</text>
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              <text>online</text>
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