Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Faculty Publications Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Creator An entity primarily responsible for making the resource Han, Jong-Eun; Lee, Han-Sol; Son, Eun-Jeong; Murthy, Hosakatte Niranjana; Park, So-Young Title A name given to the resource Changes in the dynamic profile of beneficial metabolites during Panax ginseng somatic embryogenesis Date A point or period of time associated with an event in the lifecycle of the resource 01-01-2025 Source A related resource from which the described resource is derived Industrial Crops and Products;Volume;234;Issue;;Article No.;121535; Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1016/j.indcrop.2025.121535" target="_blank" rel="noreferrer noopener">https://doi.org/10.1016/j.indcrop.2025.121535</a> <br /><br /><a href="https://www.scopus.com/pages/publications/105011375683?origin=resultslist" target="_blank" rel="noreferrer noopener">https://www.scopus.com/pages/publications/105011375683?origin=resultslist</a> Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Han J.-E., Department of Horticultural Science, Division of Animal, Horticultural and Food Sciences, Chungbuk National University, Cheongju, 28644, South Korea; Lee H.-S., Department of Horticultural Science, Division of Animal, Horticultural and Food Sciences, Chungbuk National University, Cheongju, 28644, South Korea; Son E.-J., Korea Institute of Oriental Medicine, Yuseong-daero 1672, Yuseong-gu, Daejeon, 34054, South Korea; Murthy H.N., Department of Horticultural Science, Division of Animal, Horticultural and Food Sciences, Chungbuk National University, Cheongju, 28644, South Korea, Department of Life Sciences, CHRIST (Deemed to be University), Bengaluru, 560029, India; Park S.-Y., Department of Horticultural Science, Division of Animal, Horticultural and Food Sciences, Chungbuk National University, Cheongju, 28644, South Korea Description An account of the resource In this study, we characterized the dynamic changes in the metabolite profiles of Panax ginseng during somatic embryogenesis (SE) to explore their stage-specific functional potential. We quantified phenolic compounds and amino acids using high-performance liquid chromatography (HPLC), while bioactive metabolites were identified through LC-MS/MS analysis. During SE, the total phenolic content (TPC) and total flavonoid content (TFC) significantly increased at the globular-to-torpedo (GT) stage, exhibiting enhanced antioxidant activity. Anti-inflammatory activity and cytoprotective effects peaked during the young plantlet (Yp) stage, driven by the accumulation of terpenoid metabolites, such as ginsenosides Rd and sarcostin. Additionally, at the embryogenic stem cell (ESC) stage, stress-related amino acids such as GABA and proline, along with metabolites like venlafaxine, clebopride, and nemonapride, which possess neuromodulatory properties, were distinctively accumulated. These results reveal the stage-specific metabolites and associated biological characteristics of ginseng SE, demonstrating the potential of ginseng-derived metabolites for pharmacological and nutraceutical applications. 2025 The Authors Subject The topic of the resource Embryogenic stem cells; Free amino acids; Metabolomics; Panax ginseng; Somatic embryogenesis Publisher An entity responsible for making the resource available Elsevier B.V. Relation A related resource ISSN: 9266690; CODEN: ICRDE Language A language of the resource English Type The nature or genre of the resource Article Rights Information about rights held in and over the resource All Open Access; Gold Open Access Format The file format, physical medium, or dimensions of the resource online