ItemArticle

Natural template-assisted green synthesis of cobalt oxide and its surface functionalization using ?-alanine for biological applications

Title
Natural template-assisted green synthesis of cobalt oxide and its surface functionalization using ?-alanine for biological applications
Creator
J, Helen Rose; M, Nidhin; Praveen, Parin; Agnihotri, Ananya S.; Krishnamoorthy, Ganesan
Description
The incorporation of nanotechnology into material science has brought great advancements in diverse fields like medicine, electronics, energy, and the environment. Metal oxides gained notable attention from various nanomaterials due to their unique structure and properties. Cobalt oxide nanoparticles (Co3O4) stand out especially due to their diverse properties and applications. Synthesis of metal oxides through the traditional method faces many drawbacks, such as the use of toxic chemicals, a complex procedure, and environmental and health impacts. Whereas the green method of synthesis using natural resources, followed by surface modification with amino acids, acts as a better option for metal oxide synthesis. This paper focuses on developing a green, sustainable, and scalable method for synthesising Co3O4 nanoparticles, using a natural template, gum Arabic, followed by surface functionalization of ?-alanine. Various physico-chemical characterisation techniques such as DLS, TEM, FTIR and XRD were used to study nanoparticle composition and properties. Biocompatibility studies, cell viability assays and fibroblast cell lines from human skin by Alamar Blue assay, were carried out to test the effects of synthesised nanoparticles, and optimised protocols were also used to enhance performance for particular biomedical applications. Incorporating green synthesis and advanced techniques, ?-alanine functionalized Co3O4 nanoparticles, this research points toward developing more stable, biocompatible, and reactive nanoparticles under biological conditions. and multifunctional Co3O4 nanomaterials. Overall, the current study aims at sustainability with innovation towards transformative various biological applications in healthcare, biomedicine, diagnostics, MRI, biosensors, photo-sensing agents and energy technologies while addressing significant gaps in present methodologies. 2025 Elsevier B.V.
Source
Sustainable Chemistry One World;Volume;7;Issue;;Article No.;100109;
Date
01-01-2025
Publisher
Elsevier B.V.
Subject
Biocompatibility; Cobalt oxide; Green Synthesis; Nanoparticles; ?-alanine
Coverage
J H.R., Department of Chemistry, Christ University, Karnataka, Bangalore, 560029, India; M N., Department of Chemistry, Christ University, Karnataka, Bangalore, 560029, India; Praveen P., Department of Chemistry, Christ University, Karnataka, Bangalore, 560029, India; Agnihotri A.S., Department of Chemistry, Christ University, Karnataka, Bangalore, 560029, India; Krishnamoorthy G., R & D Cell, Department of Biochemistry, Muthayammal College of Arts and Science, Tamil Nadu, Rasipuram, 637408, India
Rights
Restricted Access; Hardcopy may be available in the library
Relation
ISSN: 29503574;
Format
online
Language
English
Type
Article

Citation

J, Helen Rose; M, Nidhin; Praveen, Parin; Agnihotri, Ananya S.; Krishnamoorthy, Ganesan, “Natural template-assisted green synthesis of cobalt oxide and its surface functionalization using ?-alanine for biological applications,” CHRIST (Deemed To Be University) Institutional Repository, accessed June 18, 2026, https://archives.christuniversity.in/items/show/22454.

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