Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Faculty Publications Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Creator An entity primarily responsible for making the resource Veigas, Laveena Mariet; Ravi, Lokesh; Santhosh, G.; Kumar, Lokesh S.; Chandra, P. Nikhil; Mohan, Mothi Krishna Title A name given to the resource One pot synthesis of a novel bioactive compound employing a deep eutectic solvent grafted MWCNT system in a solventless environment Date A point or period of time associated with an event in the lifecycle of the resource 01-01-2025 Source A related resource from which the described resource is derived Scientific Reports;Volume;15;Issue;1;Article No.;26100; Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1038/s41598-025-11153-0" target="_blank" rel="noreferrer noopener">https://doi.org/10.1038/s41598-025-11153-0</a> <br /><br /><a href="https://www.scopus.com/pages/publications/105011092141?origin=resultslist" target="_blank" rel="noreferrer noopener">https://www.scopus.com/pages/publications/105011092141?origin=resultslist</a> Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Veigas L.M., Department of Sciences and Humanities, School of Engineering and Technology, Christ University, Karnataka, Bengaluru, India, St Josephs University, 36 Lalbagh Road, Karnataka, Bengaluru, 560027, India; Ravi L., Department of Biomedical Sciences, School of Health Sciences, The Apollo University, Andra Pradesh, Chittoor, 517127, India, Centre for Digital Health and Precision Medicine, The Apollo University, Andra Pradesh, Chittoor, 517127, India; Santhosh G., Department of Sciences and Humanities, School of Engineering and Technology, Christ University, Karnataka, Bengaluru, India; Kumar L.S., Department of Sciences and Humanities, School of Engineering and Technology, Christ University, Karnataka, Bengaluru, India; Chandra P.N., P.G. and Research Department of Chemistry, Sree Narayana College, Kerala, Kollam, 691001, India; Mohan M.K., Department of Sciences and Humanities, School of Engineering and Technology, Christ University, Karnataka, Bengaluru, India Description An account of the resource Heterogeneous catalysis is considered as a suitable alternative to conventional organic synthesis for the selective production of industrially significant fine chemicals. The development of supported catalysts by dispersing minimal quantities of active component can reduce production costs and enhance energy efficiency. The current work reports the development of Deep eutectic solvent (DES) modified multiwalled carbon nanotube (MWCNT) system and its activity in the Knoevenagel condensation reaction. The catalytic system was developed by grinding a very low concentration (0.83mM) of DES with desired amount of MWCNT. Various interactions of the three component DES with MWCNT were analysed by X-ray photoelectron spectroscopy (XPS). The reaction favoured a novel compound selectively with yield around 92% in solvent free medium. Anti-cancerous studies of the synthesized compound demonstrated a strong IC50 value of 15.62g/ml and a statistically calculated IC50 value of 9.8g/ml. Acridine orange/ Ethidium Bromide (AO/EB) dual fluorescence staining studies revealed that the test ligand with lowest concentration of 7.8g/ml was capable to induce apoptosis in 100% of MCF-7 cells. It is evident from the studies that the synthesized compound is a strong anticancer agent with potential to be investigated further. The Author(s) 2025. Subject The topic of the resource Cytotoxicity; Deep eutectic solvent; Grafting; Knoevenagel condensation; MWCNT Publisher An entity responsible for making the resource available Nature Research Relation A related resource ISSN: 20452322; Language A language of the resource English Type The nature or genre of the resource Article Rights Information about rights held in and over the resource All Open Access; Gold Open Access; Green Open Access Format The file format, physical medium, or dimensions of the resource online