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                <text>Faculty Publications</text>
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              <text>Agnihotri, Ananya S.; Nidhin, M.</text>
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              <text>Advanced electrochemical detection and profiling of the antihypertensive drug atenolol via a SPION-activated carbon nanocomposite interface</text>
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              <text>01-01-2025</text>
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              <text>Nanoscale Advances;Volume;7;Issue;14;pp.4397-4411</text>
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              <text>&lt;a href="https://doi.org/10.1039/d5na00314h" target="_blank" rel="noreferrer noopener"&gt;https://doi.org/10.1039/d5na00314h&lt;/a&gt; &lt;br /&gt;&lt;br /&gt;&lt;a href="https://www.scopus.com/pages/publications/105007851031?origin=resultslist" target="_blank" rel="noreferrer noopener"&gt;https://www.scopus.com/pages/publications/105007851031?origin=resultslist&lt;/a&gt;</text>
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              <text>Agnihotri A.S., Department of Chemistry, CHRIST (Deemed to be University), Bengaluru, 560029, India; Nidhin M., Department of Chemistry, CHRIST (Deemed to be University), Bengaluru, 560029, India</text>
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              <text>This study reports the synthesis of superparamagnetic iron oxide nanoparticles (SPIONs), activated carbon (AC) and SPION-AC nanocomposites using a simple hydrothermal method. Characterization of the synthesized materials includes dynamic light scattering, X-ray diffraction, field emission scanning electron microscopy, high resolution transmission electron microscopy, and vibrating sample magnetometry, along with electrochemical characterization studies such as electrochemical impedance spectroscopy. Among the SPION-AC nanocomposites, SPION-15%AC was employed to modify a glassy carbon electrode (GCE). The synergistic interaction between SPION and AC significantly enhanced the electrochemical properties of the system, leading to the development of a highly efficient platform for the detection of the antihypertensive drug atenolol (ATN) in commercial tablet samples. The sensor demonstrated excellent performance, with a linear detection range from 1.21 ?M to 285 ?M. With a low detection limit (LOD) of 0.401 ?M, the sensor offers precise quantification of ATN, making it a promising tool for improving patient care. High selectivity, reproducibility, and excellent recovery in complex pharmaceutical matrices further highlight the potential of this sensor for biomedical and clinical applications.  2025 RSC.</text>
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              <text>Royal Society of Chemistry</text>
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              <text>ISSN: 25160230;</text>
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              <text>All Open Access; Gold Open Access; Green Open Access</text>
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